Results 51 to 60 of about 778,750 (338)

Structure of cytochrome a3-Cua3 couple in cytochrome c oxidase as revealed by nitric oxide binding studies [PDF]

, 1979
The addition of NO to oxidized cytochrome c oxidase (ferrocytochrome c:oxygen oxidoreductase, EC 1.9.3.1) causes the appearance of a high-spin heme electron paramagnetic resonance (EPR) signal due to cytochrome a3. This suggests that NO coordinates to Cu{
Bocian, David F., Brudvig, Gary W., Chan, Sunney I., Stevens, Tom H.   +3 more
core  

Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]

, 2002
Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh, Korsmeyer, Stanley J., Moskowitz, Michael A., Plesnila, Nikolaus, Qiu, Jianhua, Zinkel, Sandra   +5 more
core   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products

Journal of Mind and Medical Sciences, 2020
Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Nicolae Bacinschi, Ina Pogonea, Lilia Podgurschi, Maria Mihalachi-Anghel, Emil Ștefănescu, Bogdan Socea, Marin Chianu   +6 more
doaj   +1 more source

Effect of Salts on the Conformational Dynamics of the Cytochrome P450 OleP

Molecules, 2023
Cytochrome P450 OleP catalytic activity is strongly influenced by its structural dynamic conformational behavior. Here, we combine equilibrium-binding experiments with all-atom molecular dynamics simulations to clarify how different environments affect ...
Maria Laura De Sciscio, Alessandro Nicola Nardi, Giacomo Parisi, Giovanni Bulfaro, Antonella Costanzo, Elena Gugole, Cécile Exertier, Ida Freda, Carmelinda Savino, Beatrice Vallone, Linda Celeste Montemiglio, Marco D’Abramo   +11 more
doaj   +1 more source

Photosynthetic cytochrome c550

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2012
Cytochrome c550 (cyt c550) is a membrane component of the PSII complex in cyanobacteria and some eukaryotic algae, such as red and brown algae. Cyt c550 presents a bis-histidine heme coordination which is very unusual for monoheme c-type cytochromes. In PSII, the cyt c550 with the other extrinsic proteins stabilizes the binding of Cl(-) and Ca(2+) ions
José M. Ortega, Fernando Guerrero, Diana Kirilovsky, Diana Kirilovsky, Aurelio Serrano, Mercedes Roncel   +5 more
openaire   +5 more sources

Cytochromes P450 [PDF]

The Arabidopsis Book, 2002
There are 272 cytochrome P450 genes (including 26 pseudogenes) in the Arabidopsis genome. P450s thus form one of the largest families of proteins in higher plants. This explosion of the P450 family is thought to have occurred via gene duplication and conversion, and to result from the need of sessile plants to adapt to a harsh environment and to ...
Danièle, Werck-Reichhart, Søren, Bak, Suzanne, Paquette   +2 more
openaire   +2 more sources

A Structural Model of the Cytochrome c Reductase/Oxidase Supercomplex from Yeast Mitochondria [PDF]

, 2007
Mitochondrial respiratory chain complexes are arranged in supercomplexes within the inner membrane. Interaction of cytochrome c reductase (complex III) and cytochrome c oxidase (complex IV) was investigated in Saccharomyces cerevisiae. Projection maps at
Allen, Berry, Boumans, Cruciat, DeLano, Dudkina, Dudkina, Dudkina, Dudkina, Giraud, Guex, Harris, Heinemeyer, Khalimonchuk, Kim, Lange, Lee, Ludtke, Mannella, Meisinger, Minauro-Sanmiguel, Neuhoff, Paumard, Pearce, Penczek, Pfeiffer, Roberts, Saraste, Schwerzmann, Schäfer, Schägger, Schägger, Schägger, Schägger, Stroh, Sunderhaus, Tsukihara, Van Heel, Van Heel, Wittig, Wittig, Zerbetto, Zhang, Zhang   +43 more
core   +5 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

The identification of histidine ligands to cytochrome a in cytochrome c oxidase [PDF]

, 1985
A histidine auxotroph of Saccharomyces cerevisiae has been used to metabolically incorporate [1,3-15N2] histidine into yeast cytochrome c oxidase. Electron nuclear double resonance (ENDOR) spectroscopy of cytochrome a in the [15N]histidine-substituted ...
Chan, Sunney I., Martin, Craig T., Scholes, Charles P.   +2 more
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