Results 151 to 160 of about 280,021 (209)

NDUFA4 Deletion Upregulates VDAC1 to Promote Mitochondrial Damage, Endoplasmic Reticulum Expansion, and Neuronal Apoptosis. [PDF]

Hum Mutat
Li L, Fu F, Li R, Zhou H, Huang R, Lu J, Guo F, Chen H, Lei T, Han J, Zhen L, Pan M, Li D, Liao C.   +13 more
europepmc   +1 more source

Silymarin attenuates oxidative, inflammatory and apoptotic damage induced by a fungicide mixture in rat liver, kidney and brain. [PDF]

Toxicol Rep
Salem HS, Gouda AMR, Essam NM, El-Bahnasy HT.   +3 more
europepmc   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Isosteric Engineering of Enzymes: Overcoming Activity–Stability Trade‐Offs by Site‐Selective CH → N Substitutions

Angewandte Chemie, EarlyView.
Coupling biosynthetic noncanonical amino acid production with genetic code expansion enables site‐specific incorporation of azatryptophans into PET‐degrading enzymes (PETases). By isosteric single‐atom editing of a conserved tryptophan, AzaPETases break the activity–stability trade‐off, delivering higher catalytic efficiency at elevated temperature and
Elwy H. Abdelkader, Haocheng Qianzhu, Gottfried Otting, Thomas Huber   +3 more
wiley   +2 more sources

<i>Ageratina adenophora</i> aqueous extract impairs <i>Ascaris suum</i> egg embryonation and infectivity via disruption of metabolic and detoxification pathways. [PDF]

Front Vet Sci
Wang L, Wang W, He J, Shu F, Ma J, Yang J, Zou F.   +6 more
europepmc   +1 more source

Exendin-4 protects brain endothelial cell damage against hyperammonemic condition. [PDF]

Biochem Biophys Rep
Ahn SY, Jo D, Choi SY, Song J.
europepmc   +1 more source

Aggregation of Phosphates Enhances Enzyme Activity in Aqueous Solution. [PDF]

Chemphyschem
Bajpayee S, Murugan V, Price WS, Rana S, Beves JE.   +4 more
europepmc   +1 more source

Energetics and Ecological Implications of Bacterial Electron Transport Chains. [PDF]

Environ Microbiol Rep
Xie N, Brown AM, Wang X.
europepmc   +1 more source

Contributions of ABC Transporters and Cytochrome P450s to the Tolerance in <i>Antheraea pernyi</i> Against Beta-Cypermethrin. [PDF]

Insects
Zhang T, Chen X, Chen J, Liu P, Liu F, Chen M, Xu L, Zhao S, Li X.   +8 more
europepmc   +1 more source

<i>SfCYP6AN4</i>-Mediated Spinetoram Resistance and RNA Pesticide Application in <i>Spodoptera frugiperda</i>. [PDF]

Insects
Yuan L, Yu D, Wang J, Li Y, Dai Y, Xiao H, Zhang Z.   +6 more
europepmc   +1 more source