Results 181 to 190 of about 283,147 (286)

A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells

Angewandte Chemie, EarlyView.
A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim, Huichao Zhao, Anders Bodholt Nielsen, Nino Wili, Niels Chr. Nielsen, Joseph A. Lyons, Rajeshwar Prosad Mookerjee, Brigitte Städler   +7 more
wiley   +2 more sources

Intracranial Pressure Reduction Is Associated with Mitochondrial OPA1 and Cytochrome c Release in the Retinas of AQP1-Null Mice. [PDF]

Brain Sci
Zhang Z, Wu S, Liu K, Zhang J, Liu Q, Wang N, Xue H.   +6 more
europepmc   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

Single‐Atom Iron‐Catalyzed Oxidative Esterification: From Methylarenes to the Upcycling of Polystyrene and Lignin‐Derived Feedstocks

Angewandte Chemie, EarlyView.
Heterogeneous iron‐catalyzed environmentally benign and sustainable CH‐oxidative esterification methodology has been developed for the synthesis of esters. This challenging reaction has been achieved by the rational design of specific single atom iron‐based catalyst with Fe‐N4 active centers, which empowered the oxidative esterification of methyl and ...
Zhuang Ma, Binyu Zhang, Hui Yang, Yue Hu, Junzheng Yu, Yanbin Cui, Jun Zhao, Matthias Beller, Rajenahally V. Jagadeesh   +8 more
wiley   +2 more sources

Single-cell transcriptomics identifies ergothioneine as a mitochondrial protector to prevent AKI-to-CKD progression. [PDF]

PLoS One
Peng J, Chen J, Qian Z, Han M, Chen L.
europepmc   +1 more source

Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration

Angewandte Chemie, EarlyView.
The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti, Hannah Dreisbach, Rémi Corlay, Clara Weber, Tamara Reiter, Wael Elaily, Bastian Daniel, Klaus Zangger, Pedro A. Sánchez‐Murcia, Mélanie Hall   +9 more
wiley   +2 more sources

The association of ABCB1, CYP2C19 and CYP2C9 combined activity with clopidogrel resistance in patients with recurrent ischemic stroke. [PDF]

Pharmacogenomics J
Deiman B, Hermans M, de Rijk M, Bras A, Scharnhorst V.   +4 more
europepmc   +1 more source

Circulating Mitochondrial DNA Aggravates Post-Ischemic Functional and Metabolic Recovery in an Isolated Rat Heart Model of Donation After Circulatory Death. [PDF]

Int J Mol Sci
Sanz MN, Arnold M, Segiser A, Hofmann M, Siepe M, Longnus SL.   +5 more
europepmc   +1 more source

Pulmonary Exposure to Copper Oxide Nanoparticles Induces Systemic Inflammation, Oxidative Stress, and Prothrombotic Responses in BALB/c Mice. [PDF]

Int J Nanomedicine
Ferdous Z, Beegam S, Zaaba NE, Elzaki O, Greish YE, Nemmar A.   +5 more
europepmc   +1 more source

Optimized bacterial expression of a synthetic BRIL antibody. [PDF]

Acta Crystallogr F Struct Biol Commun
Cooper BF, Isom GL.
europepmc   +1 more source