Results 121 to 130 of about 604,858 (259)

Engineering Extracellular Vesicles Derived from 3D Cultivation of BMSCs Enriched with HGF Ameliorate Sepsis‐Induced Lung Epithelial Barrier Damage

open access: yesAdvanced Science, EarlyView.
3D culture of MSCs upregulates gene expression of matrix metalloproteinases (MMPs), growth factors (GFs), and increases the production of extracellular vesicles (EVs). Proteomic analysis reveals 642 upregulated proteins in 3D‐EVs, including HGF. These 3D‐EVs, enriched with HGF, protect lung epithelial cells from apoptosis and barrier damage in septic ...
Yong Chen   +9 more
wiley   +1 more source

Generation of a High‐Precision Whole Liver Panorama and Cross‐Scale 3D Pathological Analysis for Hepatic Fibrosis

open access: yesAdvanced Science, EarlyView.
Using the MOSTtechnology and whole‐liver Nissl staining method, a multi‐structural 3D pathological panorama of liver fibrosis is obtained. The damaged sinusoids, steatotic hepatocytes, and collagen deposition are all concentrated in pericentral areas.
Xiaochuan Zhang   +13 more
wiley   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway

open access: yesAngewandte Chemie, EarlyView.
Gromomycins represent a novel class of pentacyclic triterpene antibiotics with a unique biosynthetic pathway independent of the squalene route. These compounds exhibit potent activity against drug‐resistant Gram‐positive pathogens, including MRSA, and their unprecedented cyclization mechanism provides new insight into bacterial triterpene biosynthesis.
Stepan Tistechok   +11 more
wiley   +2 more sources

meso‐Free Porphyrinoids

open access: yesAsian Journal of Organic Chemistry, EarlyView.
meso‐Free porphyrinoids are recognized as a versatile platform for further functionalization and oligomerization. The synthesis and characteristic features of such meso‐free porphyrinoids are reviewed. Abstract meso‐Unsubstituted (meso‐free) porphyrins have been an effective platform for creating versatile peripherally functionalized porphyrins and ...
Takayuki Tanaka   +2 more
wiley   +1 more source

Isotope Techniques in Chemical Wastewater Treatment: Opportunities and Uncertainties

open access: yesAngewandte Chemie, EarlyView.
In this review, we would first introduce basic knowledge about isotopic compounds and then scrutinize the physical and chemical influence induced by isotope changes. Special attention will be paid to the uncertainties in explaining the isotope results.
Hongyu Zhou   +7 more
wiley   +2 more sources

MOLECULAR DYNAMICS STUDY OF CYTOCHROME C – LIPID COMPLEXES

open access: yesEast European Journal of Physics, 2017
The interactions between a mitochondrial hemoprotein cytochrome c (cyt c) and the model lipid membranes composed of zwitterionic lipid phosphatidylcholine (PC) and anionic lipids phosphatidylglycerol (PG), phosphatidylserine (PS) or cardiolipin (CL) were
V. Trusova   +4 more
doaj  

Home - About - Disclaimer - Privacy