Results 191 to 200 of about 20,306,851 (378)

Nanoplastics Enhance Transmembrane Transport and Uptake of Carcinogens: Transcriptional Changes and the Effects of Weathering

open access: yesAdvanced Science, EarlyView.
Nanoplastics exposed to defined weathering conditions are systematically investigated as vectors for polycyclic aromatic hydrocarbons (PAHs). This investigation demonstrates significant potential for enhancing PAH uptake and transport in an intestinal membrane model.
Erik B. Schiferle   +5 more
wiley   +1 more source

Preparation of Cytochrome c with the Aid of Paper Electrophoresis. [PDF]

open access: bronze, 1952
Sven Paléus   +5 more
openalex   +1 more source

Tailoring Chemical Microenvironment of Iron‐Triad Electrocatalysts for Hydrogen Production by Water Electrolysis

open access: yesAdvanced Energy Materials, EarlyView.
Iron‐triad‐based materials are attracting attention for green hydrogen production via water electrolysis due to their favorable electronic and flexible chemical properties, enabling the tailoring of electrochemical performance. This review covers the basics of water electrolysis, challenges in catalyst evaluation, and recent advances in tuning iron ...
Jean Marie Vianney Nsanzimana   +8 more
wiley   +1 more source

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

open access: yesAngewandte Chemie, EarlyView.
AZD0156, an ATM kinase inhibitor in clinical development, shows promising multistage antiplasmodial activity by targeting Plasmodium falciparum phosphatidylinositol 4‐kinase (PfPI4Kβ). With an improved specificity profile relative to other PfPI4Kβ inhibitors and moderate efficacy in a P.
John G. Woodland   +33 more
wiley   +2 more sources

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

open access: yesAggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang   +6 more
wiley   +1 more source

A Comment on the Ultraviolet Light Absorption Spectrum of Cytochrome c. [PDF]

open access: bronze, 1954
K. G. Paul   +3 more
openalex   +1 more source

Genetics of Response to ECT, TMS, Ketamine and Esketamine

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Treatment‐resistant mood disorders are often managed with intensive interventions that include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ketamine, and esketamine, but the role of genetics in clinical response to those interventions is yet to be clearly determined.
Clio E. Franklin   +18 more
wiley   +1 more source

LC‐MS and High‐Throughput Data Processing Solutions for Lipid Metabolic Tracing Using Bioorthogonal Click Chemistry

open access: yesAngewandte Chemie, EarlyView.
This study introduces an integrated analytical and bioinformatics platform for high‐throughput tracing of lipid metabolism using bioorthogonal alkyne fatty acids and optimized LC‐MS workflow. Applied to human fibrosarcoma cells, the method traced fatty acid metabolism, revealing nuances in sphingolipid routing and metabolic bottlenecks, highlighting ...
Palina Nepachalovich   +7 more
wiley   +2 more sources

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