Results 211 to 220 of about 649,169 (309)

Structural mechanism of proton pumping by ba3-type cytochrome c oxidase

Neutze R, Johannesson J, Zorić D, Vallejos A, Kabbinale A, Sandelin E, Glerup J, Ghosh S, Finke A, Bjelčić M, Rönnholm J, Ostojić LL, Dahl P, Beale E, Cirelli C, Dworkowski F, Bacellar C, Johnson P, Ozerov D, Batyuk A, Boutet S, Gate G, Kupitz C, Peck A, Poitevin F, Sierra R, Lisova S, Wallentin C, Brändén G.   +28 more
europepmc   +1 more source

The role of vitamin C in melanoma cell death via activation of cytochrome C and TNF-α protein expression. [PDF]

Sci Rep
Sutedja EK, Arianto TR, Elgianda GS, Sutedja E, Lesmana R, Suwarsa O, Hindritiani R, Achdiat PA, Gunawan H, Setiabudiawan B.   +9 more
europepmc   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Cytochrome c Oxidase Subunit COX4-1 Reprograms Erastin-Induced Cell Death from Ferroptosis to Apoptosis: A Transmitochondrial Study. [PDF]

Antioxidants (Basel)
Oliva CR, Flor S, Griguer CE.
europepmc   +1 more source

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

Arthritis &Rheumatology, EarlyView.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven, Avery H. Welfley, Priyanka P. Brahmachary, Mark Greenwood, Donald F. Smith, Brian Bothner, Ronald K. June   +6 more
wiley   +1 more source

Correction: Essential requirement of cytochrome c release for caspase activation by procaspase-activating compound defined by cellular models. [PDF]

Cell Death Dis
Seervi M, Joseph J, Sobhan PK, Bhavya BC, Santhoshkumar TR.   +4 more
europepmc   +1 more source

Transient Transfection of Rolling‐Circle Amplified DNA in Biomanufacturing‐Relevant Mammalian Cell Lines: A Comparison of Transfection Conditions for Optimal Protein Expression

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Rolling‐circle amplification (RCA) is a completely synthetic and rapid mechanism for scaling‐up bulk DNA that eliminates requirements for large‐scale bacterial fermentation. Several reports have described the surprising ability of large unprocessed (hyperbranched) rolling circle‐amplified DNA (RCA DNA) to effectively transfect cultured cells ...
Evelina Loghin, Erik Kvam, Lisa Lowery, Nathan Hudson, Jenny Keen, Brian Davis, Roger B. Dodd, Christine Surrette, John Nelson   +8 more
wiley   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Novel Variants in Sperm Mitochondrial Cytochrome C Oxidase II (<i>MT-CO2</i>) Gene Associated with Asthenozoospermia in Jordan. [PDF]

Curr Issues Mol Biol
Al Zoubi MS, AlQuraan RN, Al-Smadi A, AlSmadi MA, AbuAlArja M, Alkaraki AK, Al-Trad B, Al-Zoubi RM, Al-Batayneh K.   +8 more
europepmc   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source