Results 191 to 200 of about 373,312 (259)

Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa, Hayato Shimazaki, Shunji Igarashi, Yoshiki Tagawa, Naoki Hisada, Hiromi Shibasaki   +5 more
wiley   +1 more source

Putative long range mossy fiber sprouting and regional cytochrome c oxidase alteration in the hippocampus of patients with mesial temporal lobe epilepsy. [PDF]

Sci Rep
Tu T, Wan L, Zhang QL, Yang C, Zhou HS, Sun ZP, Long HY, Tang BS, Pan A, Tu E, Wang J, Yang ZQ, Li ZY, Yan XX.   +13 more
europepmc   +1 more source

Optimal dosing for vascular anomalies paediatric patients with population pharmacokinetic model of sirolimus

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Sirolimus is currently used off‐label for paediatric patients with vascular anomalies. However, the optimal dosage regimen for paediatric patients remains controversial. This study aimed to determine the optimal dosing regimen of sirolimus in these patients using a population pharmacokinetic (PK) model.
Seongmee Jeong, Jungryul Kim, Woojin Jung, Jiyeon Jeon, Hyeongjun Jo, Kyoung‐Bin Ryu, Ja‐Young Hong, Kwan Soo Kim, Seongjun Yang, Hee Young Ju, Hwi‐yeol Yun, Jung‐woo Chae, Keon Hee Yoo, Soyoung Lee   +13 more
wiley   +1 more source

Dynamic assessment of the allocation of copper to cytochrome c oxidase using size-exclusion chromatography (SEC) combined with inductively coupled plasma mass spectrometry (ICP-MS). [PDF]

J Biol Chem
Secic D, Bischoff ME, Schmidt L, Panmanee W, Yang J, Meller J, Vest KE, Cunningham JT, Landero JA, Czyzyk-Krzeska MF.   +9 more
europepmc   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

The Role of the Surface Functionalities in the Electrocatalytic Activity of Cytochrome C on Graphene-Based Materials. [PDF]

Nanomaterials (Basel)
Quintero-Jaime AF, Cazorla-Amorós D, Morallón E.   +2 more
europepmc   +1 more source

Efficiency of the cytochrome c oxidase subunit II gene for the delimitation of termite species (Blattodea: Isoptera) in the state of Paraíba, northeastern Brazil. [PDF]

PLoS One
Paulino Monteiro SR, Carvalho A, Ferreira RR, Figueirêdo RECR, Vasconcellos A, Koroiva R.   +5 more
europepmc   +1 more source

Cytochrome c oxidase inactivation in Physcomitrium patens reveals that respiration coordinates plant metabolism. [PDF]

Plant Cell
Vera-Vives AM, Mellon M, Gurrieri L, Westhoff P, Segalla A, Tan SL, Bizzotto E, Campanaro S, Sparla F, Weber APM, Alboresi A, Morosinotto T.   +11 more
europepmc   +1 more source

Dimerization-induced conformational transitions of yeast iso-1 cytochrome <i>c</i>. [PDF]

Magn Reson Lett
Wang Q, Sun P, Hu Q, Duan M, Zhang G, Zhan J, Yang M, Zhu Q, Yuan B, Jiang B, He L, Liu M, Zhang X, Zeng D.   +13 more
europepmc   +1 more source

Binding of Cytochrome c to CdTe Colloidal Quantum DotsInvestigation of Stoichiometry and Thermodynamics of the Nanohybrid Creation Process. [PDF]

ACS Omega
Darżynkiewicz ZM, Sławski J, Rydzy M, Grzyb J.   +3 more
europepmc   +1 more source