Fungal modular polyketide synthases (PKSs) remain largely unexplored. Functional characterization of the LasC/LasD assembly line established its role in strasseriolide C biosynthesis and suggested an unexpected strategy for chain initiation, in which a malonyl unit is transferred from the module 2 acyl carrier protein (ACP) domains to the loading ACP ...
Qiaolin Ji +5 more
wiley +2 more sources
A Cytochrome c-Containing Periplasmic Nitrate Reductase in the Acetogen Sporomusa ovata. [PDF]
Waschinger LM +4 more
europepmc +1 more source
Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray +4 more
wiley +1 more source
Sortase-mediated ligation of cytochrome c peroxidase and cytochrome c highlights the roles of dynamics and conformational specificity for interprotein electron transfer. [PDF]
Zawistowski RK, Clark JC, Crane BR.
europepmc +1 more source
COXFA4L2 upregulation preserves residual cytochrome c oxidase activity in COXFA4-related Leigh-like encephalopathy. [PDF]
Falabella M +42 more
europepmc +1 more source
Ein Biosynthese‐Gencluster aus Streptomyces sp. YIM 121038 wurde untersucht, wobei die Produktion des Sesterterpens Tibonen A und seines Oxidationsprodukts Tibonon nachgewiesen wurde. Der Cyclisierungsmechanismus zu Tibonen A wurde mittels Isotopenmarkierungsexperimenten, DFT‐Berechnungen und Eingriffen in die Enzym‐Substrat‐Wechselwirkung durch ...
Min Wang +6 more
wiley +1 more source
Ginkgolide A enhances cardiomyocyte differentiation from pluripotent stem cells by targeting cytochrome c to attenuate intrinsic apoptosis. [PDF]
Xu W +11 more
europepmc +1 more source
J. Geller, C. Meyer, M. Parker, H. Hawk
semanticscholar +1 more source
Intracranial Pressure Reduction Is Associated with Mitochondrial OPA1 and Cytochrome c Release in the Retinas of AQP1-Null Mice. [PDF]
Zhang Z +6 more
europepmc +1 more source

