Results 201 to 210 of about 40,950,057 (342)

Characterization of a Fungal Modular Polyketide Synthase System Reveals an Unusual Strategy for Polyketide Chain Initiation

open access: yesAngewandte Chemie, EarlyView.
Fungal modular polyketide synthases (PKSs) remain largely unexplored. Functional characterization of the LasC/LasD assembly line established its role in strasseriolide C biosynthesis and suggested an unexpected strategy for chain initiation, in which a malonyl unit is transferred from the module 2 acyl carrier protein (ACP) domains to the loading ACP ...
Qiaolin Ji   +5 more
wiley   +2 more sources

A Cytochrome c-Containing Periplasmic Nitrate Reductase in the Acetogen Sporomusa ovata. [PDF]

open access: yesEnviron Microbiol
Waschinger LM   +4 more
europepmc   +1 more source

IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases

open access: yesEMBO Journal, 1998
Q. Deveraux   +8 more
semanticscholar   +1 more source

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

open access: yesAngewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray   +4 more
wiley   +1 more source

COXFA4L2 upregulation preserves residual cytochrome c oxidase activity in COXFA4-related Leigh-like encephalopathy. [PDF]

open access: yesNat Commun
Falabella M   +42 more
europepmc   +1 more source

Eine Sesterterpensynthase für Tibonen und ein Cytochrom P450 für Dessen Oxidation zu Tibonon aus Streptomyces sp. YIM 121038

open access: yesAngewandte Chemie, EarlyView.
Ein Biosynthese‐Gencluster aus Streptomyces sp. YIM 121038 wurde untersucht, wobei die Produktion des Sesterterpens Tibonen A und seines Oxidationsprodukts Tibonon nachgewiesen wurde. Der Cyclisierungsmechanismus zu Tibonen A wurde mittels Isotopenmarkierungsexperimenten, DFT‐Berechnungen und Eingriffen in die Enzym‐Substrat‐Wechselwirkung durch ...
Min Wang   +6 more
wiley   +1 more source

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