Results 231 to 240 of about 40,950,057 (342)

Design of azine antioxidants for sustainable biodiesel: integrating structural characterization and molecular modeling

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract The growing global demand for sustainable energy solutions has intensified the search for renewable alternatives to fossil fuels, with biodiesel emerging as a promising candidate due to its biodegradability and lower emissions. However, its large‐scale application is limited by low oxidative stability, which compromises storage and performance.
Patricia R. S. Wenceslau   +10 more
wiley   +1 more source

Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2014
Xian-Chen Jiang   +3 more
semanticscholar   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

In silico study of cytochrome-C binding to a cardiolipin-containing membrane. [PDF]

open access: yesEur Biophys J
Muroni A   +7 more
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain   +3 more
wiley   +1 more source

Exposure to CYP2C19‐metabolized drugs following acute stroke: A longitudinal cohort study to inform implementation of CYP2C19 genotype testing

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 2C19 (CYP2C19) genotype testing is recommended to guide antiplatelet selection after ischaemic stroke and transient ischaemic attack. CYP2C19 also metabolizes several commonly prescribed non‐antiplatelet drugs. We aimed to quantify exposure to CYP2C19‐metabolized drugs in stroke patients at hospital discharge and during ...
Cleodie C. Swire   +3 more
wiley   +1 more source

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