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Heme–Protein Interactions and Functional Relevant Heme Deformations: The Cytochrome c Case
Heme proteins are known to perform a plethora of biologically important functions. This article reviews work that has been conducted on various class I cytochrome c proteins over a period of nearly 50 years.
Reinhard Schweitzer-Stenner
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Cytochrome c552 from Thermus thermophilus is one of the hot topics for creating smart biomaterials as it possesses remarkable stability, is tolerant to multiple mutations and has therefore been recently reported for a number of functionalizations upon ...
Sami Ben Aoun, Sheikh Muhammad Ibrahim
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Decoding the role of cytochrome c in metabolism of human spermatozoa by Raman imaging
The normal functioning of sperm cells requires cytochrome c in the redox balanced forms: reduced and oxidized. The oxidized form of cytochrome c is localized in the mitochondrial intermembrane space and is a part of the electron transport chain.
Halina Abramczyk +4 more
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NMR Study on the Mechanism of Cytochrome c Methionine Oxidation
Mitochondria generate reactive oxygen species (ROS) during respiration. Low levels of ROS are conducive to signal transduction, whereas excessive accumulation of ROS can lead to protein oxidative modification.
ZHAO Beibei +5 more
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Extracytoplasmic prosthetic group ligation to apoproteins: maturation of c‐type cytochromes [PDF]
SummaryIn all organisms, haem is post‐translationally and covalently attached to c apocytochromes to produce c holocytochromes via a process called c‐type cytochromes maturation, which involves numerous components. In bacteria it was not clear which of these components catalyses the extracytoplasmic haem–apocytochrome ligation per se.
Serdar, Turkarslan +2 more
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The enhanced inhibitory effect of paclitaxel (PTX) combined with hypericin (HY) on B16-F10 cells may be realized through the ROS-related cytochrome c release pathway.
Liyun Sun +3 more
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Mitochondrial Group II Introns, Cytochrome c Oxidase, and Senescence in Podospora anserina [PDF]
Podospora anserina is a filamentous fungus with a limited life span. It expresses a degenerative syndrome called senescence, which is always associated with the accumulation of circular molecules (senDNAs) containing specific regions of the mitochondrial chromosome.
O, Begel +4 more
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Background: Diabetes is a disease characterized by high levels of reactive oxygen species that trigger a series of events that culminate in programmed cell death. Terpenoids from plants used in traditional Chinese medicine have preventive and therapeutic
Tolulope A. Oyedeji +8 more
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Tissue-specific and species-specific distribution of -SH groups in cytochrome c oxidase subunits [PDF]
Cytochrome c oxidase was isolated from pig, bovine, rat and human tissues including liver, heart, diaphragm and kidney. The native and the sodium-dodecyl-sulfate (SDS)-dissociated enzymes were labelled under optimal conditions with N-ethyl-[2,3-14C]maleimide before and after reduction with dithiothreitol, separated into 13 subunits by SDS gel ...
A, Stroh, B, Kadenbach
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Cyclophosphamide (CPA) is a widely used anti-neoplastic drug, but its usage is associated with several side effects including hepatotoxicity. This study was designed to evaluate the ameliorative effect of Ganoderma lucidium (GL) extract as a natural ...
Dina R Gad El-Karim, Gamal El-Amrawi
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