Results 11 to 20 of about 279,218 (267)

Heme–Protein Interactions and Functional Relevant Heme Deformations: The Cytochrome c Case

open access: yesMolecules, 2022
Heme proteins are known to perform a plethora of biologically important functions. This article reviews work that has been conducted on various class I cytochrome c proteins over a period of nearly 50 years.
Reinhard Schweitzer-Stenner
doaj   +1 more source

An engineered thermally tolerant apo-cytochrome scaffold for metal-less incorporation of heme derivative.

open access: yesPLoS ONE, 2023
Cytochrome c552 from Thermus thermophilus is one of the hot topics for creating smart biomaterials as it possesses remarkable stability, is tolerant to multiple mutations and has therefore been recently reported for a number of functionalizations upon ...
Sami Ben Aoun, Sheikh Muhammad Ibrahim
doaj   +1 more source

Decoding the role of cytochrome c in metabolism of human spermatozoa by Raman imaging

open access: yesFrontiers in Cell and Developmental Biology, 2022
The normal functioning of sperm cells requires cytochrome c in the redox balanced forms: reduced and oxidized. The oxidized form of cytochrome c is localized in the mitochondrial intermembrane space and is a part of the electron transport chain.
Halina Abramczyk   +4 more
doaj   +1 more source

NMR Study on the Mechanism of Cytochrome c Methionine Oxidation

open access: yesChinese Journal of Magnetic Resonance, 2023
Mitochondria generate reactive oxygen species (ROS) during respiration. Low levels of ROS are conducive to signal transduction, whereas excessive accumulation of ROS can lead to protein oxidative modification.
ZHAO Beibei   +5 more
doaj   +1 more source

Extracytoplasmic prosthetic group ligation to apoproteins: maturation of c‐type cytochromes [PDF]

open access: yesMolecular Microbiology, 2006
SummaryIn all organisms, haem is post‐translationally and covalently attached to c apocytochromes to produce c holocytochromes via a process called c‐type cytochromes maturation, which involves numerous components. In bacteria it was not clear which of these components catalyses the extracytoplasmic haem–apocytochrome ligation per se.
Serdar, Turkarslan   +2 more
openaire   +2 more sources

Hypericin Enhances Paclitaxel-Induced B16-F10 Cell Apoptosis by Activating a Cytochrome c Release–Dependent Pathway

open access: yesFrontiers in Pharmacology, 2021
The enhanced inhibitory effect of paclitaxel (PTX) combined with hypericin (HY) on B16-F10 cells may be realized through the ROS-related cytochrome c release pathway.
Liyun Sun   +3 more
doaj   +1 more source

Mitochondrial Group II Introns, Cytochrome c Oxidase, and Senescence in Podospora anserina [PDF]

open access: yesMolecular and Cellular Biology, 1999
Podospora anserina is a filamentous fungus with a limited life span. It expresses a degenerative syndrome called senescence, which is always associated with the accumulation of circular molecules (senDNAs) containing specific regions of the mitochondrial chromosome.
O, Begel   +4 more
openaire   +2 more sources

Geraniol ameliorates testicular damage in diabetic rats via inhibition of redox parameters and mitochondrial-mediated apoptosis

open access: yesPharmacological Research - Modern Chinese Medicine, 2023
Background: Diabetes is a disease characterized by high levels of reactive oxygen species that trigger a series of events that culminate in programmed cell death. Terpenoids from plants used in traditional Chinese medicine have preventive and therapeutic
Tolulope A. Oyedeji   +8 more
doaj   +1 more source

Tissue-specific and species-specific distribution of -SH groups in cytochrome c oxidase subunits [PDF]

open access: yesEuropean Journal of Biochemistry, 1986
Cytochrome c oxidase was isolated from pig, bovine, rat and human tissues including liver, heart, diaphragm and kidney. The native and the sodium-dodecyl-sulfate (SDS)-dissociated enzymes were labelled under optimal conditions with N-ethyl-[2,3-14C]maleimide before and after reduction with dithiothreitol, separated into 13 subunits by SDS gel ...
A, Stroh, B, Kadenbach
openaire   +2 more sources

CYCLOPHOSPHAMIDE HEPATOTOXICITY: THE ROLE OF 4-HYDROXYNONENAL AND CYTOCHROME C OXIDASE AND THE POSSIBLE PROTECTIVE EFFECT OF GANODERMA LUCIDUM EXTRACT

open access: yesSlovenian Veterinary Research, 2019
Cyclophosphamide (CPA) is a widely used anti-neoplastic drug, but its usage is associated with several side effects including hepatotoxicity. This study was designed to evaluate the ameliorative effect of Ganoderma lucidium (GL) extract as a natural ...
Dina R Gad El-Karim, Gamal El-Amrawi
doaj   +1 more source

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