Results 221 to 230 of about 28,229,161 (299)

Advanced In Vitro Platforms for Experimental Liver Research: From Organoids and Liver‐on‐Chip to Omics and Artificial Intelligence

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hepatocytes perform essential physiological functions in the human body. Gaining more profound insight into the liver structure, diseases, and physiology by using in vitro models can help to propose more relevant clinical applications. Conventional in vitro liver models, such as two‐dimensional (2D) cell cultures, fail to adequately replicate ...
Seyedeh Kiana Teymorian, Pedram Asadi Sarabi, Abbas Piryaei, Massoud Vosough   +3 more
wiley   +1 more source

Heme handling in the system II heme lyase CcsBA from Bacteroides thetaiotaomicron. [PDF]

J Biol Inorg Chem
Seifermann J, Ilcu L, Moog C, Zhang L, Einsle O.   +4 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Wolves in Bhutan Are Part of the Ancient Himalayan Wolf (<i>Canis lupus chanco</i>) Lineage. [PDF]

Ecol Evol
Dhendup T, Sampedro A, Robinson JJ, Janečka JE, Werhahn G.   +4 more
europepmc   +1 more source

Near‐infrared light‐activated aptamer‐based nanoprobe for spatiotemporally resolved detection of L‐lactate in colorectal cancer

BMEMat, EarlyView.
A near‐infrared (NIR) light‐activated “lock‐key” nanodevice is reported for spatiotemporally resolved detection of intratumoral L‐lactate. The system stays silent until deep‐penetrating NIR light remotely unlocks its function, allowing for precise sensing within tumors.
Siyu Pan, Xuanyi Lu, Wenjie Yang, Yunhui Peng, Lingfu Deng, Shuai Zha, Xueyang Fang, Guochen Bao, Lijun Jiang   +8 more
wiley   +1 more source

A systematic review and network meta-analysis of single nucleotide polymorphisms associated with oral submucous fibrosis risk. [PDF]

Medicine (Baltimore)
Huang C, Liu J, Zeng B, Zhang L, Zhou Z, Huang X, He B, Bao M.   +7 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Drug development targeting the mitochondrial respiratory chain of Sparganum proliferum: Initial biochemical and drug discovery insights into the enigmatic helminth parasite. [PDF]

PLoS Negl Trop Dis
Enkai S, Nakano Y, Koyanagi M, Arimura Y, Kanuka H, Ishiwata K.   +5 more
europepmc   +1 more source

Ant Diversity of the Xisha Islands: Community Structure, Exotic Species Colonization, and Ecological Functions in a Tropical Coral Archipelago

Biological Diversity, EarlyView.
The first inventory of ants from the Xisha Islands of the South China Sea was compiled, revealing 21 species: 70% native and 30% exotic. Anthropogenic disturbance primarily drove exotic colonization, whereas island area showed weak positive effects on species richness. Most ants were omnivorous, with key mutualistic and seed‐dispersal roles.
Hua‐Yan Chen, Zhi‐Xuan Liu, Zheng‐Hui Xu, Rui‐Chong Wang, Shi‐Xiao Luo   +4 more
wiley   +1 more source

Effects of Four Marine Toxins on Murine Hepatic Biotransformation Enzymes. [PDF]

Toxins (Basel)
Soto de Jesus J, González-Keelan C, Meléndez PA, Cadilla CL, Contreras J, Jiménez-Vélez BD.   +5 more
europepmc   +1 more source