Results 21 to 30 of about 2,436,389 (378)

Synthesis of haem cytochrome c prosthetic group from δ-aminolaevulinate by the cell sap from rat liver [PDF]

open access: bronzeBiochemical Journal, 1977
To determine whether the prosthetic group of cytochrome c is synthesized and linked to the apoprotein in the cytosol or in connexion with the endoplasmic reticulum, we have studied the incorporation in vitro of δ-amino[14C]laevulinate into porphyrin compounds and cytochrome c by the cell sap from rat liver.
Carmen Sáez De Córdova   +2 more
openalex   +4 more sources

Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease [PDF]

open access: greenNeuroscience Letters, 2009
Heme-a, is the heme prosthetic group of cytochrome c oxidase (COX), the terminal complex of the mitochondrial electron transport chain. We measured heme-a levels in postmortem brain tissue from nine patients diagnosed with dementia: Alzheimer's disease (AD) was the primary diagnosis in five, AD/diffuse Lewy body disease (DLBD) was diagnosed in two ...
Barney E. Dwyer   +6 more
openalex   +3 more sources

Influence of B16/F10 melanoma growth variant on the level of cytochrome C in mitochondria in various organs of female mice

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2021
Introduction. Cytochrome C in mitochondria transfers electrons from complex III to complex IV, and it is a signaling molecule in the apoptosis realization.The objective was to evaluate the level of cytochrome C in cell mitochondria in various organs of ...
E. M. Frantsiyants   +4 more
doaj   +1 more source

Knockdown of prohibitin 2 promotes apoptosis in non-small cell lung cancer cell line A549 [PDF]

open access: yesJichu yixue yu linchuang, 2023
Objective To explore mechanism of prohibitin 2(PHB2) inhibition on the apoptosis of non-small cell lung cancer cell line A549. Methods For stable knockdown of PHB2, A549 strain was infected with lentiviruses. A549 cells with PHB2 depletion were
ZHANG Jing, YANG Zigeng, WEI Hongmei, NING Haihong, XUE Xixi, JIN Ling, WU Bin
doaj   +1 more source

Neat1 decreases neuronal apoptosis after oxygen and glucose deprivation

open access: yesNeural Regeneration Research, 2022
Studies have shown that downregulation of nuclear-enriched autosomal transcript 1 (Neat1) may adversely affect the recovery of nerve function and the increased loss of hippocampal neurons in mice.
Wei-Na Chai   +10 more
doaj   +1 more source

Human chorionic gonadotropin attenuates amyloid-β plaques induced by streptozotocin in the rat brain by affecting cytochrome c-ir neuron density [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2019
Objective(s): Amyloid β plaques, in Alzheimer’s disease, are deposits in different areas of the brain such as prefrontal cortex, molecular layer of the cerebellum, and the hippocampal formation.
Emsehgol Nikmahzar   +5 more
doaj   +1 more source

Functional state of cardiomyocyte mitochondria in malignant process in presence of comorbid pathology in experiment

open access: yesЮжно-Российский онкологический журнал, 2021
Purpose of the study. An analysis of indices of free radical oxidation and respiration of mitochondria of heart cells in a malignant process in presence of diabetes mellitus and chronic neurogenic pain in experimental animals.Materials and methods.
E. M. Frantsiyants   +12 more
doaj   +1 more source

Heme–Protein Interactions and Functional Relevant Heme Deformations: The Cytochrome c Case

open access: yesMolecules, 2022
Heme proteins are known to perform a plethora of biologically important functions. This article reviews work that has been conducted on various class I cytochrome c proteins over a period of nearly 50 years.
Reinhard Schweitzer-Stenner
doaj   +1 more source

Vibrational structure of the formyl group on heme a. Implications on the properties of cytochrome c oxidase

open access: bronzeBiophysical Journal, 1991
Resonance Raman spectra have been recorded for heme a derivatives in which the oxygen atom of the formyl group has been isotopically labeled and for Schiff base derivatives of heme a in which the Schiff base nitrogen has been isotopically labeled. The 14N-15N isotope shift in the C = N stretching mode of the Schiff base is close to the theoretically ...
Sae‐Won Han   +3 more
openalex   +3 more sources

An engineered thermally tolerant apo-cytochrome scaffold for metal-less incorporation of heme derivative.

open access: yesPLoS ONE, 2023
Cytochrome c552 from Thermus thermophilus is one of the hot topics for creating smart biomaterials as it possesses remarkable stability, is tolerant to multiple mutations and has therefore been recently reported for a number of functionalizations upon ...
Sami Ben Aoun, Sheikh Muhammad Ibrahim
doaj   +1 more source

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