Results 91 to 100 of about 396,597 (394)

Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

Advanced Healthcare Materials, EarlyView.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin, Sean P. Doidge, Eiman Aleem, Suela Kellici, Steven Dunn, Claire Atkinson, Philip D. Howes   +6 more
wiley   +1 more source

Stability of Bovine Cytochrome c Oxidase as Studied After Exposure to High Hydrostatic Pressure

Acta Medica, 2004
Structural and functional stability of bovine cytochrome c oxidase as a function of exposure to high hydrostatic pressure is reported. The pressure affects the stability of monomeric and dimeric enzyme quite differently.
Jana Staničová, Andrej Musatov, Neal C. Robinson   +2 more
doaj   +1 more source

Rate-limiting Step Preceding Cytochrome c Release in Cells Primed for Fas-mediated Apoptosis Revealed by Analysis of Cellular Mosaicism of Respiratory Changes [PDF]

, 2001
In the present work, Jurkat cells undergoing anti-Fas antibody (anti-Fas)-triggered apoptosis exhibited in increasing proportion a massive release of cytochrome c from mitochondria, as revealed by double-labeling confocal immunofluorescence microscopy ...
Attardi, Giuseppe, Hájek, Petr, Villani, Gaetano   +2 more
core  

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Inactivation of Cytochrome-c with Glucose Oxidase

Journal of Enzyme Inhibition and Medicinal Chemistry, 2004
A novel reaction of cytochrome-c from the horse heart with the enzyme glucose oxidase from Aspergillus niger (EC 1.1.3.4), in acidic media is described. Glucose oxidase is able to induce a rapid, profound and irreversible physico-chemical change in cytochrome-c, under anaerobic conditions and in the presence of glucose.
Julijan Kandrač, Draginja Peričin, Vladimir Leskovac, Svetlana Trivić   +3 more
openaire   +4 more sources

Effect of pre-irradiation with different doses, wavelengths, and application intervals of low-level laser therapy on cytochrome c oxidase activity in intact skeletal muscle of rats

Lasers in Medical Science, 2014
Modulation of cytochrome c oxidase activity has been pointed as a possible key mechanism for low-level laser therapy (LLLT) in unhealthy biological tissues.
G. M. Albuquerque-Pontes, R. Vieira, S. S. Tomazoni, Claudia Caires, V. Nemeth, A. A. Vanin, L. Santos, H. Pinto, R. L. Marcos, J. Bjordal, Paulo de Tarso Camillo de Carvalho, E. C. Leal-Junior   +11 more
semanticscholar   +1 more source

Incorporation of cytochrome oxidase into cardiolipin bilayers and induction of nonlamellar phases. [PDF]

, 1990
Cytochrome oxidase from beef heart has been lipid-substituted with beef heart cardiolipin. The lipid phase behavior and protein aggregation state of the reconstituted complexes have been studied with 31P NMR, freeze-fracture electron microscopy, and ...
Knowles, P., Marsh, D., Powell, G.
core   +2 more sources

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

Advanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban, Hoon Yi, Jaejin Park, Yunuo Huang, Ki Jun Yu, Woon‐Hong Yeo   +5 more
wiley   +1 more source

Prognostic relevance of cytochrome C oxidase in primary glioblastoma multiforme.

PLoS ONE, 2013
Patients with primary glioblastoma multiforme (GBM) have one of the lowest overall survival rates among cancer patients, and reliable biomarkers are necessary to predict patient outcome.
Corinne E Griguer, Alan B Cantor, Hassan M Fathallah-Shaykh, G Yancey Gillespie, Amber S Gordon, James M Markert, Ivan Radovanovic, Virginie Clement-Schatlo, Chevis N Shannon, Claudia R Oliva   +9 more
doaj   +1 more source

Radical formation in cytochrome c oxidase

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2011
The formation of radicals in bovine cytochrome c oxidase (bCcO), during the O(2) redox chemistry and proton translocation, is an unresolved controversial issue. To determine if radicals are formed in the catalytic reaction of bCcO under single turnover conditions, the reaction of O(2) with the enzyme, reduced by either ascorbate or dithionite, was ...
Kyoko Shinzawa-Itoh, Gary J. Gerfen, Syun Ru Yeh, Shinya Yoshikawa, Denis L. Rousseau, Tsuyoshi Egawa, Michelle Yu   +6 more
openaire   +3 more sources