Results 101 to 110 of about 541,087 (354)

Applying synthetic biology strategies to bioelectrochemical systems

Electrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract Although the past 20 years have seen significant advances in tailoring materials for improving the performance of bioelectrochemical systems, recently, there have been efforts in utilizing the synthetic biology toolkit for engineering organisms for bioelectrochemical systems.
Fangyuan Dong, Olja Simoska, Erin Gaffney, Shelley D. Minteer   +3 more
wiley   +1 more source

Intracytoplasmic Copper Homeostasis Controls Cytochrome c Oxidase Production

mBio, 2014
Copper is an essential micronutrient used as a metal cofactor by a variety of enzymes, including cytochrome c oxidase (Cox). In all organisms from bacteria to humans, cellular availability and insertion of copper into target proteins are tightly ...
S. Ekici, S. Turkarslan, Grzegorz Pawlik, A. Dancis, N. Baliga, H. Koch, F. Daldal   +6 more
semanticscholar   +1 more source

Inactivation of Cytochrome-c with Glucose Oxidase

Journal of Enzyme Inhibition and Medicinal Chemistry, 2004
A novel reaction of cytochrome-c from the horse heart with the enzyme glucose oxidase from Aspergillus niger (EC 1.1.3.4), in acidic media is described. Glucose oxidase is able to induce a rapid, profound and irreversible physico-chemical change in cytochrome-c, under anaerobic conditions and in the presence of glucose.
Julijan Kandrač, Draginja Peričin, Vladimir Leskovac, Svetlana Trivić   +3 more
openaire   +4 more sources

Photo‐Biomodulation of the Hippocampus Using Near‐Infrared Laser to Enhance Cognitive Function in Mice

Advanced Science, EarlyView.
Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan, Han‐Wen Gu, Yan‐Bo Zhou, Sophie Ma, Daqing Ma, Pan‐Miao Liu, Jian‐Jun Yang   +6 more
wiley   +1 more source

Phenotypic assessment of Cox10 variants and their implications for Leigh Syndrome

BMC Research Notes
Objectives Cox10 is an enzyme required for the activity of cytochrome c oxidase. Humans who lack at least one functional copy of Cox10 have a form of Leigh Syndrome, a genetic disease that is usually fatal in infancy. As more human genomes are sequenced,
Thomas-Shadi Voges, Eun Bi Lim, Abigail MacKenzie, Kyle Mudler, Rebecca DeSouza, Nmesoma E. Onyejekwe, Stephen D. Johnston   +6 more
doaj   +1 more source

Molecular interface of S100A8 with cytochrome b558 and NADPH oxidase activation. [PDF]

PLoS ONE, 2012
S100A8 and S100A9 are two calcium binding Myeloid Related Proteins, and important mediators of inflammatory diseases. They were recently introduced as partners for phagocyte NADPH oxidase regulation.
Sylvie Berthier, Minh Vu Chuong Nguyen, Athan Baillet, Marc-André Hograindleur, Marie-Hélène Paclet, Benoît Polack, Françoise Morel   +6 more
doaj   +1 more source

Respiratory Flexibility in Response to Inhibition of Cytochrome c Oxidase in Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy, 2014
We report here a series of five chemically diverse scaffolds that have in vitro activities on replicating and hypoxic nonreplicating bacilli by targeting the respiratory bc1 complex in Mycobacterium tuberculosis in a strain-dependent manner.
Kriti Arora, Bernardo Ochoa-Montaño, Patricia S. Tsang, T. Blundell, S. Dawes, V. Mizrahi, T. Bayliss, Claire J. Mackenzie, Laura A. T. Cleghorn, Peter C. Ray, P. Wyatt, E. Uh, Jinwoo Lee, C. Barry, H. Boshoff   +14 more
semanticscholar   +1 more source

Radical formation in cytochrome c oxidase

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2011
The formation of radicals in bovine cytochrome c oxidase (bCcO), during the O(2) redox chemistry and proton translocation, is an unresolved controversial issue. To determine if radicals are formed in the catalytic reaction of bCcO under single turnover conditions, the reaction of O(2) with the enzyme, reduced by either ascorbate or dithionite, was ...
Kyoko Shinzawa-Itoh, Gary J. Gerfen, Syun Ru Yeh, Shinya Yoshikawa, Denis L. Rousseau, Tsuyoshi Egawa, Michelle Yu   +6 more
openaire   +3 more sources

Impact of Salmonella genome rearrangement on gene expression

Evolution Letters, Volume 6, Issue 6, Page 426-437, December 2022., 2022
Abstract In addition to nucleotide variation, many bacteria also undergo changes at a much larger scale via rearrangement of their genome structure (GS) around long repeat sequences. These rearrangements result in genome fragments shifting position and/or orientation in the genome without necessarily affecting the underlying nucleotide sequence.
Emma V. Waters, Liam A. Tucker, Jana K. Ahmed, John Wain, Gemma C. Langridge   +4 more
wiley   +1 more source

Deprenyl, an old drug with new anticancer potential: Mini review [PDF]

arXiv, 2021
The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv