Results 101 to 110 of about 270,701 (335)

Mutations in SURF1 are important genetic causes of Leigh syndrome in Slovak patients

open access: yesEndocrine Regulations, 2018
Objectives. Leigh syndrome is a progressive early onset neurodegenerative disease typically presenting with psychomotor regression, signs of brainstem and/or basal ganglia disease, lactic acidosis, and characteristic magnetic resonance imaging findings ...
Danis Daniel   +7 more
doaj   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

open access: yesAngewandte Chemie International Edition, EarlyView.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer   +4 more
wiley   +1 more source

Cytochrome c oxidase in cytochrome c oxidase-deficient mutant strains of Neurospora crassa.

open access: yesJournal of Biological Chemistry, 1981
Three mutant strains of Neurospora crassa, previously characterized as cytochrome c oxidase deficient, were found to possess this respiratory enzyme. The mitochondrial cytochrome contents of logarithmic phase cells of wild type (74A) and the respiration-deficient strains mi-3, cya-4-23, and cya-5-34 were investigated with low temperature difference ...
R. Brambl, S. Stade
openaire   +3 more sources

Metal‐Mediated Protein Engineering within Live Cells

open access: yesChemistry – An Asian Journal, Volume 20, Issue 6, March 17, 2025.
This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
wiley   +1 more source

COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase

open access: yesCell Reports, 2019
Summary: In eukaryotes, cellular respiration is driven by mitochondrial cytochrome c oxidase (CcO), an enzyme complex that requires copper cofactors for its catalytic activity.
Shivatheja Soma   +12 more
doaj  

The small protein CydX is required for function of cytochrome bd oxidase in Brucella abortus

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
A large number of hypothetical genes potentially encoding small proteins of unknown function are annotated in the Brucella abortus genome. Individual deletion of 30 of these genes identified four mutants, in BAB1_0355, BAB2¬_0726, BAB2_0470 and ...
Yao-Hui eSun   +5 more
doaj   +1 more source

The effect of sodium nitroprusside in scaffolds for synergetic gas‐photothermal therapy of osteosarcoma

open access: yesBMEMat, EarlyView.
The PCLA‐SNP scaffolds can produce photothermal agents in situ under ultraviolet radiation. Then, the scaffold can release nitric oxide gas spontaneously and generate hyperthermia under near‐infrared laser to enhance ablation of bone tumors. Furthermore, the calcium and iron ions released from PCLA‐SNP scaffolds can accelerate bone regeneration ...
Shaojie Dong   +9 more
wiley   +1 more source

Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase

open access: yesGenome Biology, 2012
Orthology is a central tenet of comparative genomics and ortholog identification is instrumental to protein function prediction. Major advances have been made to determine orthology relations among a set of homologous proteins.
R. Szklarczyk   +10 more
semanticscholar   +1 more source

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