Results 11 to 20 of about 270,701 (335)
Multiple Mechanisms Regulate Eukaryotic Cytochrome C Oxidase
Cells, 2021 Cytochrome c oxidase (COX), the rate-limiting enzyme of mitochondrial respiration, is regulated by various mechanisms. Its regulation by ATP (adenosine triphosphate) appears of particular importance, since it evolved early during evolution and is still ...
Rabia Ramzan +2 more
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Nature Communications, 2021 Cytochrome c oxidase is a fundamental enzyme of life and its mechanism is not fully understood yet. Here, the authors present four cryo-EM structures of different intermediate states, which suggest an alternative cytochrome c oxidase reaction cycle.
F. Kolbe +5 more
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Cytochrome c Oxidase Deficiency [PDF]
Pediatric Research, 1990 Cytochrome c oxidase (COX) is a complex enzyme composed of 13 subunits, three of which are encoded by the mitochondrial DNA (mtDNA). The other 10 subunits are encoded by the nuclear DNA, synthesized in the cytoplasm, and transported into the mitochondria.
Dlmauro S. +9 more
openaire +3 more sources
Rcf1 Modulates Cytochrome c Oxidase Activity Especially Under Energy-Demanding Conditions
Frontiers in Physiology, 2020 The mitochondrial respiratory chain is assembled into supercomplexes. Previously, two respiratory supercomplex-associated proteins, Rcf1 and Rcf2, were identified in Saccharomyces cerevisiae, which were initially suggested to mediate supercomplex ...
Hannah Dawitz +5 more
doaj +1 more source
A biochemical approach to study the role of the terminal oxidases in aerobic respiration in Shewanella oneidensis MR-1. [PDF]
PLoS ONE, 2014 The genome of the facultative anaerobic γ-proteobacterium Shewanella oneidensis MR-1 encodes for three terminal oxidases: a bd-type quinol oxidase and two heme-copper oxidases, a A-type cytochrome c oxidase and a cbb 3-type oxidase.
Sébastien Le Laz +5 more
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Activity of respiratory chain cytochrome complexes and cytochromes content in the rat kidney mitochondria under different nutrients content in a diet [PDF]
The Ukrainian Biochemical Journal, 2023 An important role in ensuring the functioning of the respiratory chain belongs to the cytochrome part, which includes complexes III (ubiquinol-cytochrome c oxidoreductase) and IV (cytochrome c oxidase). The key components of these enzymatic complexes are
H. P. Kopylchuk, O. M. Voloshchuk
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Multilayered polyelectrolyte microcapsules: interaction with the enzyme cytochrome C oxidase. [PDF]
PLoS ONE, 2014 Cell-sized polyelectrolyte capsules functionalized with a redox-driven proton pump protein were assembled for the first time. The interaction of polyelectrolyte microcapsules, fabricated by electrostatic layer-by-layer assembly, with cytochrome c oxidase
Laura Pastorino +9 more
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Cytochrome-C Oxidase Deficiency
Definitions, 2020 The severity of cytochrome c oxidase deficiency varies widely among affected individuals, even among those in the same family. People who are mildly affected tend to have muscle weakness (myopathy) and poor muscle tone (hypotonia) with no other related ...
semanticscholar +1 more source
Functions of Cytochrome c Oxidase Assembly Factors
International Journal of Molecular Sciences, 2020 Cytochrome c oxidase is the terminal complex of eukaryotic oxidative phosphorylation in mitochondria. This process couples the reduction of electron carriers during metabolism to the reduction of molecular oxygen to water and translocation of protons ...
Shane A Watson, Gavin Peter McStay
semanticscholar +1 more source
Cholate Disrupts Regulatory Functions of Cytochrome c Oxidase
Cells, 2021 Cytochrome c oxidase (CytOx), the oxygen-accepting and rate-limiting enzyme of mitochondrial respiration, binds with 10 molecules of ADP, 7 of which are exchanged by ATP at high ATP/ADP-ratios.
Rabia Ramzan +4 more
doaj +1 more source