Results 41 to 50 of about 389,313 (377)
Structure of the intact 14-subunit human cytochrome c oxidase
Cell Research, 2018 Respiration is one of the most basic features of living organisms, and the electron transport chain complexes are probably the most complicated protein system in mitochondria.
Shuai Zong +5 more
semanticscholar +1 more source
, 2020 The mitochondrial cytochrome c oxidase, the terminal enzyme of the respiratory chain, contains heme and copper centers for electron transfer. The conserved COX2 subunit contains the CuA site, a binuclear copper center.
Aich, A. +11 more
core +1 more source
EMBO Journal, 2016 Mitochondrial cytochrome c oxidase (CcO) transfers electrons from cytochrome c (Cyt.c) to O2 to generate H2O, a process coupled to proton pumping. To elucidate the mechanism of electron transfer, we determined the structure of the mammalian Cyt.c–CcO ...
S. Shimada +9 more
semanticscholar +1 more source
Q-band electron nuclear double resonance (ENDOR) and X-band EPR of the sulfobetaine 12 heat-treated cytochrome c oxidase complex [PDF]
, 1997 Heat treatment of the bovine cytochrome c oxidase complex in the zwitterionic detergent sulfobetaine 12 (SB-12) results in loss of subunit III and the appearance of a type II copper center as characterized by electron paramagnetic resonance (EPR ...
Chan, Sunney I. +4 more
core +1 more source
Mitochondrial cytochrome c oxidase: catalysis, coupling and controversies.
Biochemical Society Transactions, 2017 Mitochondrial cytochrome c oxidase is a member of a diverse superfamily of haem-copper oxidases. Its mechanism of oxygen reduction is reviewed in terms of the cycle of catalytic intermediates and their likely chemical structures.
P. Rich
semanticscholar +1 more source
Flux control of cytochrome c oxidase in human skeletal muscle [PDF]
, 2000 In the present work, by titrating cytochrome c oxidase (COX) with the specific inhibitor KCN, the flux control coefficient and the metabolic reserve capacity of COX have been determined in human saponin-permeabilized muscle fibers. In the presence of the
Attardi, Giuseppe +5 more
core +1 more source
Cytochrome oxidase in a cytochrome oxidaserich submitochondrial membrane [PDF]
, 1969 1. A cytochrome oxidase-rich submitochondrial membrane (green membrane) was obtained from beef heart mitochondria after extraction of flavoproteins, cytochrome b, Cll C, etc. by treating with deoxycholate and potassium chloride. 2. The green membrane was
Seki, Shuji
core +1 more source
Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice
Nature Communications, 2016 Mutations in the translational activator of cytochrome c oxidase subunit I (TACO1) causes cytochrome c oxidase deficiency and Leigh Syndrome in patients.
Tara R. Richman +11 more
doaj +1 more source
Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency. [PDF]
PLoS ONE, 2017 Sirtuins are NAD+ dependent deacetylases, which regulate mitochondrial energy metabolism as well as cellular response to stress. The NAD/NADH-system plays a crucial role in oxidative phosphorylation linking sirtuins and the mitochondrial respiratory ...
Arne Björn Potthast +3 more
doaj +1 more source
New colorimetic methods for the estimation of cytochrome c oxidase and of cytochrome c-cyto-chrome oxidase system [PDF]
, 1958 New colorimetric methods for the estimation of the activities of cytochrome c oxidase and of cytochrome c-cytochrome oxidase system in tissue homogenates are described, using neotetrazolium chloride in the presence of p-phenylenediamine with or without ...
Oda, Takuzo +2 more
core +1 more source