Morphology of mitochondria and cell respiration,pt.2. [PDF]
With the purpose to elucidate the relation between the enzyme activity and the morphology of mitochondria the author carried out histochemical and biochemical investigations of cytochrome oxidase and succinic dehydrogenase activities of liver cells ...
Haba, Kyoichi
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Origin of Jordanian honeybees Apis mellifera (Hymenoptera: Apidae) using amplified mitochondrial DNA
The honeybee (Apis mellifera L.) has a large number of geographic subspecies distributed across Europe, Africa and Asia, many of which have been described. This identification is important for bee breeding and preserving honeybee biodiversity.
Shahera ZAITOUN+2 more
doaj +1 more source
Cytochrome c Oxidase Inhibition by ATP Decreases Mitochondrial ROS Production
This study addresses the eventual consequence of cytochrome c oxidase (CytOx) inhibition by ATP at high ATP/ADP ratio in isolated rat heart mitochondria. Earlier, it has been demonstrated that the mechanism of allosteric ATP inhibition of CytOx is one of
Rabia Ramzan+6 more
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Rcf1 and Rcf2, Members of the Hypoxia-induced Gene 1 Protein Family, Are Critical Components of the Mitochondrial Cytochrome bc1-cytochrome Oxidase Supercomplex [PDF]
We report that Rcf1 (formerly Aim31), a member of the conserved hypoxia-induced gene 1 (Hig1) protein family, represents a novel component of the yeast cytochrome bc1-cytochrome c oxidase (COX) supercomplex.
Furness, Andrew+4 more
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Nuclear mutations affecting mitochondrial structure and function in Chlamydomonas [PDF]
Wild type cells of the green alga Chlamydomonas reinhardtii can grow in the in the dark by taking up and respiring exogenously supplied acetate. Obligate photoautotrophic (dark dier, dk) mutants of this alga have been selected which grow at near wild ...
Boynton, J. E.+2 more
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Differentiation and cell density upregulate cytochrome c levels in megakaryoblastic cell lines: Implications for analysis of CYCS-associated thrombocytopenia. [PDF]
Mutations in the cytochrome c gene (CYCS) cause autosomal dominant thrombocytopenia by an unknown mechanism. While attempting to generate megakaryoblastic cell lines exogenously expressing cytochrome c variants, we discovered that endogenous cytochrome c
Lily Ong+2 more
doaj +1 more source
New methods for the histochemical and cytochemical demonstrtion of cytochrome c oxidase and of cytochrome c- cytochrome oxidase system [PDF]
New histochemical and cytochemical methods for the demonstration of cytochrome c oxidase and of cytochrome c-cytochrome oxidase system are described, using neotetrazolium chloride in the presence of p phenylenediamine with or without additional ...
Oda, Takuzo+2 more
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From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Cytochrome c oxidase, the terminal enzyme of the respiratory chain, is assembled from mitochondria- and nuclear-encoded subunits. The MITRAC complex represents the central assembly intermediate during this process as it receives imported subunits and ...
Sven Dennerlein+8 more
doaj +1 more source
Abstract When a purified bovine heart cytochrome c oxidase was polarographically assayed by a method involving initial contact of the enzyme with Tween 80, very high turnover numbers were observed at low enzyme concentrations, e.g. 5 to 10 mµm cytochrome a3.
K. Ganapathy, H.S. Mason
openaire +3 more sources