Results 61 to 70 of about 541,087 (354)
Laminar model for the joint development of ocular dominance columns and CO blobs in V1 [PDF]
arXiv, 2022 In this paper, we present a multi--layer, activity--dependent model for the joint development of ocular dominance (OD) columns and cytochrome oxidase (CO) blobs in primate primary visual cortex (V1). For simplicity, we focus on layers 4C and 2/3 with both layers receiving direct thalamic inputs and layer 4C sending vertical projections to layer 2/3 ...
arxiv
Catching proteins in liquid helium droplets [PDF]
Phys. Rev. Lett. 105, 133402 (2010), 2010 An experimental approach is presented that allows for the incorporation of large mass/charge selected ions in liquid helium droplets. It is demonstrated that droplets can be efficiently doped with a mass/charge selected amino acid as well as with the much bigger m$\approx$12 000 amu protein Cytochrome C in selected charge states.
arxiv +1 more source
Higd1a is a positive regulator of cytochrome c oxidase
Proceedings of the National Academy of Sciences of the United States of America, 2015 Significance We identified hypoxia-inducible domain family, member 1A (Higd1a) as a positive regulator of cytochrome c oxidase (CcO). CcO, the terminal component of the mitochondrial electron transfer system, reductively converts molecular oxygen to ...
T. Hayashi +24 more
semanticscholar +1 more source
Journal of Biological Chemistry, 1970 Abstract When a purified bovine heart cytochrome c oxidase was polarographically assayed by a method involving initial contact of the enzyme with Tween 80, very high turnover numbers were observed at low enzyme concentrations, e.g. 5 to 10 mµm cytochrome a3.
K. Ganapathy, H.S. Mason
openaire +3 more sources
FEBS Open Bio, EarlyView.FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
Hydrophilic Chitosan Derivatives: Synthesis and Applications
Chemistry – A European Journal, Volume 28, Issue 67, December 1, 2022., 2022 A benign and low‐cost alternative for fossil‐fuel‐sourced polymers, chitosan has tremendous potential because of its bioactivity, biocompatibility, biodegradability, and low toxicity. Synthetic pathways for chitosan derivatives with improved water solubility, and their associated applications, are explored. With the change in global direction towards a
Erez Cohen, Elena Poverenov
wiley +1 more source
Protein Adsorption into Mesopores: A Combination of Electrostatic Interaction, Counterion Release and van der Waals Forces [PDF]
Langmuir 30, 2729-2737 (2014), 2015 Bovine heart cytochrome c has been immobilized into the mesoporous silica host material SBA-15 in both its native folded and urea-unfolded state. The comparison of the two folding states' behavior casts doubt on the commonly used explanation of cytochrome c adsorption, i.e. the electrostatic interaction model.
arxiv +1 more source
Human mitochondrial COX1 assembly into cytochrome c oxidase at a glance
Journal of Cell Science, 2015 Mitochondria provide the main portion of cellular energy in form of ATP produced by the F1Fo ATP synthase, which uses the electrochemical gradient, generated by the mitochondrial respiratory chain (MRC). In human mitochondria, the MRC is composed of four
Sven Dennerlein, P. Rehling
semanticscholar +1 more source
Protonmotive cooperativity in cytochrome c oxidase
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2004 Cooperative linkage of solute binding at separate binding sites in allosteric proteins is an important functional attribute of soluble and membrane bound hemoproteins. Analysis of proton/electron coupling at the four redox centers, i.e. Cu(A), heme a, heme a(3) and Cu(B), in the purified bovine cytochrome c oxidase in the unliganded, CO-liganded and CN-
Papa, Sergio +3 more
openaire +6 more sources
Upregulation of Mitochondrial Content in Cytochrome c Oxidase Deficient Fibroblasts. [PDF]
PLoS ONE, 2016 Cytochrome-c-oxidase (COX) deficiency is a frequent cause of mitochondrial disease and is associated with a wide spectrum of clinical phenotypes. We studied mitochondrial function and biogenesis in fibroblasts derived from the Cohen (CDs) rat, an animal ...
Aviram Kogot-Levin +6 more
doaj +1 more source