Results 71 to 80 of about 541,087 (354)
Metabolites, 2022 Although often effective at treating newly diagnosed glioblastoma (GBM), increasing evidence suggests that chemo- and radiotherapy-induced alterations in tumor metabolism promote GBM recurrence and aggressiveness, as well as treatment resistance.
Claudia R. Oliva +3 more
doaj +1 more source
A biosynthetic model of cytochrome c oxidase as an electrocatalyst for oxygen reduction
Nature Communications, 2015 Creating an artificial functional mimic of the mitochondrial enzyme cytochrome c oxidase (CcO) has been a long-term goal of the scientific community as such a mimic will not only add to our fundamental understanding of how CcO works but may also pave the
S. Mukherjee +5 more
semanticscholar +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Prodrugs of the Archetypal Dynamin Inhibitor Bis‐T‐22
ChemMedChem, Volume 17, Issue 24, December 16, 2022., 2022 The Bis‐T series of compounds comprise some of the most potent inhibitors of dynamin GTPase activity yet reported, such as Bis‐T‐22 (2). The catechol moieties are believed to limit cell permeability, rendering these compounds largely inactive in cells.
Luke R. Odell +6 more
wiley +1 more source
Oxidative Rearrangements of the Alkaloid Intermediate Geissoschizine
Angewandte Chemie, EarlyView.19E‐geissoschizine is a key precursor in the biosynthesis of monoterpene indole alkaloids such as strychnine, ibogaine, and vinblastine. Using enzymatic assays and gene silencing, three CYPs were identified from C. roseus that oxidize this compound to four alkaloid scaffolds: strychnos, sarpagan, akuammiline, and mavacurane. Mutational analysis reveals
Mohamed O. Kamileen +6 more
wiley +2 more sources
DNA metabarcoding and the cytochrome c oxidase subunit I marker: not a perfect match
Biology Letters, 2014 DNA metabarcoding enables efficient characterization of species composition in environmental DNA or bulk biodiversity samples, and this approach is making significant and unique contributions in the field of ecology.
B. Deagle +4 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Cellulosic emulsions as multi‐cargo agriculture formulations. Pickering emulsions stabilized by cellulose acetate particles provide an effective platform for delivering a range of agricultural cargoes, including plant growth‐promoting bacteria and agrochemicals.
Mariam Sohail +10 more
wiley +1 more source
Brain Stimulation, 2021 Background: Transcranial laser stimulation is a novel method of noninvasive brain stimulation found safe and effective for improving prefrontal cortex neurocognitive functions in healthy young adults.
Celeste L. Saucedo +6 more
doaj
Malaria Journal, 2022 Background Copper is an essential metal for living organisms as a catalytic co-factor for important enzymes, like cytochrome c oxidase the final enzyme in the electron transport chain.
Abdulmalik Abdullahi Salman +1 more
doaj +1 more source
Regulation of Oxidative Phosphorylation of Liver Mitochondria in Sepsis
Cells, 2022 The link between liver dysfunction and decreased mitochondrial oxidative phosphorylation in sepsis has been clearly established in experimental models. Energy transduction is plastic: the efficiency of mitochondrial coupling collapses in the early stage ...
Pierre Eyenga +3 more
doaj +1 more source