Results 1 to 10 of about 138,479 (226)
Cytochrome c-peroxidase modulates ROS homeostasis to regulate the sexual mating of Sporisorium scitamineum [PDF]
Microbiology Spectrum, 2023 Sugarcane smut, caused by the basidiomycetous fungus Sporisorium scitamineum, is a global fungal disease resulting in substantial economic losses. Our previous research has highlighted the significant role of reactive oxide species (ROS) in the sexual ...
Enping Cai +7 more
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Evolutionary Approaches to Study Cytochrome c Peroxidase
CHIMIA, 2001 Directed molecular evolution of enzymes and proteins has emerged as an extremely powerful method to create proteins with novel properties, both for practical applications as well as for mechanistic studies.
André Iffland +3 more
doaj +5 more sources
Leishmania major peroxidase is a cytochrome c peroxidase. [PDF]
Biochemistry, 2012 Leishmania major peroxidase (LmP) exhibits both ascorbate and cytochrome c peroxidase activities. Our previous results illustrated that LmP has a much higher activity against horse heart cytochrome c than ascorbate, suggesting that cytochrome c may be the biologically important substrate.
Jasion VS, Poulos TL.
europepmc +5 more sources
The response of glutathione oxidase and cytochrome c to exercise training and sodium selenite in the heart tissue of male rats [PDF]
Biochemistry and Biophysics ReportsIntroduction: Exercise training combined with supplements may be effective in enhancing antioxidant defense and mitochondrial function. Therefore, this study aimed to determine the response of glutathione peroxidase and cytochrome c to forced resistance ...
Farah Nameni, Fatemeh Elikaei
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In-silico assessment of protein-protein electron transfer. a case study: cytochrome c peroxidase--cytochrome c. [PDF]
PLoS Computational Biology, 2013 The fast development of software and hardware is notably helping in closing the gap between macroscopic and microscopic data. Using a novel theoretical strategy combining molecular dynamics simulations, conformational clustering, ab-initio quantum ...
Frank H Wallrapp +2 more
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Informatics in Medicine Unlocked, 2018 Mutations in cytochrome c (Cyt c) have been reported in tuning peroxidase activity, which in-turn cause Cyt c release from mitochondria and early apoptosis. However, the molecular tuning mechanism underlying this activity remains elusive.
Gurusamy Muneeswaran +5 more
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Two-dimensional infrared spectroscopic study of cytochrome c peroxidase activity in deep eutectic solvent [PDF]
Structural Dynamics, 2019 Deep eutectic solvents (DESs) prepared by mixing hydrogen-bond donor and acceptor molecules have been found to be of use in several applications. Recently, it was shown that DESs can enhance the peroxidation activity of cytochrome c.
Koji Osawa +4 more
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Cytochrome c Peroxidase–Cytochrome c Complexes
, 2015 The yeast cytochrome c peroxidase (CCP)–cytochrome c (cytc) electron transfer system has been critically important in deciphering the molecular level details of protein–protein interactions and electron transfer. The crystal structure of the CCP–cytc together with a number mutagenesis, enzymological, and spectroscopic studies have provided a detailed ...
T.L. Poulos
+5 more sources
Engineering ascorbate peroxidase activity into cytochrome c peroxidase. [PDF]
Biochemistry, 2008 Cytochrome c peroxidase (CCP) and ascorbate peroxidase (APX) have very similar structures, and yet neither CCP nor APX exhibits each other's activities with respect to reducing substrates. APX has a unique substrate binding site near the heme propionates where ascorbate H-bonds with a surface Arg and one heme propionate (Sharp et al. (2003) Nat. Struct.
Meharenna YT +3 more
europepmc +4 more sources
Structural basis for cytochrome c Y67H mutant to function as a peroxidase.
PLoS ONE, 2014 The catalytic activity of cytochrome c (cyt c) to peroxidize cardiolipin to its oxidized form is required for the release of pro-apoptotic factors from mitochondria, and for execution of the subsequent apoptotic steps.
Wenxian Lan +8 more
doaj +2 more sources