Results 21 to 30 of about 69,108 (276)

Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle

Nature Communications, 2023
Skeletal muscle is more resilient to ischemia-reperfusion injury than other organs. Tissue specific post-translational modifications of cytochrome c (Cytc) are involved in ischemia-reperfusion injury by regulating mitochondrial respiration and apoptosis.
Paul T. Morse, Gonzalo Pérez-Mejías, Junmei Wan, Alice A. Turner, Inmaculada Márquez, Hasini A. Kalpage, Asmita Vaishnav, Matthew P. Zurek, Philipp P. Huettemann, Katherine Kim, Tasnim Arroum, Miguel A. De la Rosa, Dipanwita Dutta Chowdhury, Icksoo Lee, Joseph S. Brunzelle, Thomas H. Sanderson, Moh H. Malek, David Meierhofer, Brian F. P. Edwards, Irene Díaz-Moreno, Maik Hüttemann   +20 more
doaj   +1 more source

Hydrogen-rich water treatment improves fresh-cut Gastrodia elata quality by regulating reactive oxygen species metabolism and energy metabolism during low temperature storage

Frontiers in Sustainable Food Systems, 2023
The application of hydrogen-rich water (HRW) can extend the shelf life of fruits and vegetables. This study aims to investigate the effects of HRW on the quality of fresh-cut Gastrodia elata during low-temperature (4°C) storage. The results indicate that
Boyu Dong, Boyu Dong, Dequan Zhu, Dequan Zhu, Qiuping Yao, Qiuping Yao, Fangfang Da, Fangfang Da, Yulong Chen, Yulong Chen, Xiaochun Ding   +10 more
doaj   +1 more source

Effects of Laser Radiation on Mitochondria and Mitochondrial Proteins Subjected to Nitric Oxide

Frontiers in Medicine, 2018
The biological roles of heme and nonheme nitrosyl complexes in physiological and pathophysiological conditions as metabolic key players are considered in this study. Two main physiological functions of protein nitrosyl complexes are discussed—(1) a depot
Anatoly N. Osipov, Tatiana V. Machneva, Evgeny A. Buravlev, Evgeny A. Buravlev, Yury A. Vladimirov, Yury A. Vladimirov   +5 more
doaj   +1 more source

Acute Alcohol Tissue Damage: Protective Properties of Betaine

Journal of Renal and Hepatic Disorders, 2021
Teenage binge drinking is a major health issue; however, there is a paucity of data on liver injury. Herein, we investigated how acute ethanol affects juvenile hepatic cells through changes in oxidative stress, apoptosis, and liver function, as well as ...
Lucy Petagine, Hannah Everitt, Victor Preedy, Roy Sherwood, Vinood Patel   +4 more
doaj   +1 more source

The complex of cytochrome c and cytochrome c peroxidase: The end of the road?

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2011
Cytochrome c (Cc) and cytochrome c peroxidase (CcP) form a physiological complex in the inter-membrane space of yeast mitochondria, where CcP reduces hydrogen peroxide to water using the electrons provided by ferrous Cc. The Cc-CcP system has been a popular choice of study of interprotein biological electron transfer (ET) and in understanding dynamics ...
Volkov, A.N., Worrall, J.A.R., Nicholls, P.   +2 more
openaire   +4 more sources

Structural basis for cytochrome c Y67H mutant to function as a peroxidase.

PLoS ONE, 2014
The catalytic activity of cytochrome c (cyt c) to peroxidize cardiolipin to its oxidized form is required for the release of pro-apoptotic factors from mitochondria, and for execution of the subsequent apoptotic steps.
Wenxian Lan, Zhonghua Wang, Zhongzheng Yang, Tianlei Ying, Xu Zhang, Xiangshi Tan, Maili Liu, Chunyang Cao, Zhong-Xian Huang   +8 more
doaj   +1 more source

Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis

Cells, 2021
Prostate cancer is the second leading cause of cancer-related death in men. Two classic cancer hallmarks are a metabolic switch from oxidative phosphorylation (OxPhos) to glycolysis, known as the Warburg effect, and resistance to cell death. Cytochrome c
Viktoriia Bazylianska, Hasini A. Kalpage, Junmei Wan, Asmita Vaishnav, Gargi Mahapatra, Alice A. Turner, Dipanwita Dutta Chowdhury, Katherine Kim, Paul T. Morse, Icksoo Lee, Joseph S. Brunzelle, Lisa Polin, Prabal Subedi, Elisabeth I. Heath, Izabela Podgorski, Katrin Marcus, Brian F.P. Edwards, Maik Hüttemann   +17 more
doaj   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source

Sulfite oxidase activity of cytochrome c: Role of hydrogen peroxide

Biochemistry and Biophysics Reports, 2016
In humans, sulfite is generated endogenously by the metabolism of sulfur containing amino acids such as methionine and cysteine. Sulfite is also formed from exposure to sulfur dioxide, one of the major environmental pollutants.
Murugesan Velayutham, Craig F. Hemann, Arturo J. Cardounel, Jay L. Zweier   +3 more
doaj   +1 more source

Comprehensive acetyl-proteomic analysis of Cytospora mali provides insight into its response to the biocontrol agent Bacillus velezensis L-1

Frontiers in Sustainable Food Systems, 2022
Cytospora mali is an important factor for apple valsa canker, and Bacillus veleznesis L-1 is an effective biocontrol agent against apple valsa canker.
Pingping Sun, Qiang Ma, Lei Zhang
doaj   +1 more source