Results 61 to 70 of about 69,108 (276)
Advanced Materials, EarlyView.A schematic illustration of how noble metals can be used to create nanoparticles (NPs) or nanoclusters (NCs). Noble metal NPs, due to their plasmonic properties, enable photothermal therapy and surface‐enhanced Raman scattering (SERS). In contrast, NCs, which lack a plasmonic resonance band, exhibit fluorescence, making them ideal for bioimaging ...
David Esporrín‐Ubieto +3 more
wiley +1 more source
Angewandte Chemie, EarlyView.When cellular iron is low, bacterioferritin (Bfr) releases its stored iron through a reductive process dependent on the [2Fe–2S] ferredoxin Bfd. Why accessing stored iron should depend on an iron‐requiring protein when iron is scarce is unclear. Here, we show that the Bfd [2Fe–2S] cluster is sensitive to oxidative stress, suggesting that it may act as ...
Justin M. Bradley +4 more
wiley +2 more sources
Informatics in Medicine Unlocked, 2018 Mutations in cytochrome c (Cyt c) have been reported in tuning peroxidase activity, which in-turn cause Cyt c release from mitochondria and early apoptosis. However, the molecular tuning mechanism underlying this activity remains elusive.
Gurusamy Muneeswaran +5 more
doaj
Cytochrome c Peroxidase, a Mitochondrial Enzyme of Yeast
Journal of Biological Chemistry, 1966 Abstract The intracellular distribution of cytochrome c peroxidase was studied in aerobically grown Saccharomyces carlsbergensis. Most of the cytochrome c peroxidase present in the yeast cells was found to be associated with well preserved mitochondria. This enzyme is readily released from mitochondria upon disruption of their structures.
Takashi Yonetani, Tomoko Ohnishi
openaire +3 more sources
The low-affinity complex of cytochrome c and its peroxidase [PDF]
Nature Communications, 2015 AbstractThe complex of yeast cytochrome c peroxidase and cytochrome c is a paradigm of the biological electron transfer (ET). Building on seven decades of research, two different models have been proposed to explain its functional redox activity. One postulates that the intermolecular ET occurs only in the dominant, high-affinity protein–protein ...
Van De Water, Karen +2 more
openaire +3 more sources
Spatial Coordination Structure‐Driven Enzyme‐Like Selectivity in Single‐Atom Nanozymes
Advanced Materials, EarlyView.Sun et al. reviews recent progress in enhancing the enzyme‐like catalytic selectivity of SAzymes through the rational design of their spatial coordination structures. They emphasize the structure‐activity relationships of various attributes of these coordination structures in promoting selective catalytic behavior, the strategic design of coordination ...
Qijun Sun +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.We have engineered the heme biosynthetic pathway in E. coli to develop an efficient cofactor supplementation system for hemoproteins. Through the incorporation of the heterogeneous C4 pathway, the engineered cells significantly increase the expression levels of active holohemoproteins and enhance the efficiency of whole‐cell and lysate‐based ...
Shunsuke Kato +6 more
wiley +2 more sources
Cytochrome c Peroxidase–Cytochrome c Complexes
, 2015 The yeast cytochrome c peroxidase (CCP)–cytochrome c (cytc) electron transfer system has been critically important in deciphering the molecular level details of protein–protein interactions and electron transfer. The crystal structure of the CCP–cytc together with a number mutagenesis, enzymological, and spectroscopic studies have provided a detailed ...
openaire +3 more sources
Advanced Therapeutics, EarlyView.Transcranial photobiomodulation (PBM) enhances spatial working memory in healthy rats under both continuous and alternating stimulation protocols. At the neural level, PBM modulates cytochrome c oxidase activity, increases prefrontal and hippocampal synaptic markers, and induces region‐specific c‐Fos expression. These effects suggest improved cognitive
Candela Zorzo +6 more
wiley +1 more source
Advanced Science, EarlyView.The apple susceptibility‐related LRR‐RLK MdRLKT21 competitively binds to fungal sRNA effectors and subsequently activates defenses by salvaging the expression of MdRLKT1 and MdRLKT2 and thereby releasing the resistance protein MdRFP1. These findings provide new insights into the molecular mechanism by which plants counteract pathogen‐secreted sRNA ...
Mingliang Lei +7 more
wiley +1 more source