Results 71 to 80 of about 138,479 (226)

Miconazole for the treatment of vulvovaginal candidiasis. In vitro, in vivo and clinical results. Review of the literature

Journal of Obstetrics and Gynaecology, 2023
At concentrations achieved following systemic administration, the primary effect of imidazoles and triazoles on fungi is inhibition of 14-α-sterol demethylase, a microsomal cytochrome P450 (CYP) enzyme. Imidazoles and triazoles impair the biosynthesis of
Pedro Antonio Regidor, Manopchai Thamkhantho, Chenchit Chayachinda, Santiago Palacios   +3 more
doaj   +1 more source

Crystalline Cytochrome c Peroxidase and Complex ES

Journal of Biological Chemistry, 1966
Cytochrome c peroxidase, purified from bakers' yeast, has been obtained in crystalline form. Upon the addition of hydroperoxides, crystals of the enzyme were readily converted to those of Complex ES without modification of their crystalline form. As judged from their size, shape, and stability, these crystals of cytochrome c peroxidase and Complex ES ...
T, Yonetani, B, Chance, S, Kajiwara
openaire   +2 more sources

Perfluorooctanesulfonate Mediates Renal Tubular Cell Apoptosis through PPARgamma Inactivation. [PDF]

PLoS ONE, 2016
Perfluorinated chemicals (PFCs) are ubiquitously distributed in the environments including stainless pan-coating, raincoat, fire extinguisher, and semiconductor products. The PPAR family has been shown to contribute to the toxic effects of PFCs in thymus,
Li-Li Wen, Chien-Yu Lin, Hsiu-Chu Chou, Chih-Cheng Chang, Hau-Yin Lo, Shu-Hui Juan   +5 more
doaj   +1 more source

Low Temperature Photo-oxidation of Chloroperoxidase Compound II [PDF]

, 2010
Oxidation of the heme-thiolate enzyme chloroperoxidase (CPO) from Caldariomyces fumago with peroxynitrite (PN) gave the Compound II intermediate, which was photo-oxidized with 365 nm light to give a reactive oxidizing species.
Bennett, Brian, Fung, Leslie W. -M., Horner, John A., Newcomb, Martin, Sheng, Xin, Yuan, Xinting   +5 more
core   +2 more sources

Analysis of radiation-induced cell death in head and neck squamous cell carcinoma and rat liver maintained in microfluidic devices [PDF]

, 2013
Objective The aim of this study was to investigate how head and neck squamous cell carcinoma (HNSCC) tissue biopsies maintained in a pseudo in vivo environment within a bespoke microfluidic device respond to radiation treatment.
Burcombe R, Cai L, Eriksson D, Eriksson D, Fernberg JO, Hattersley SM, Hattersley SM, Ianzini F, Jemal A, Kamotani Y, Kroemer G, Lee P, Ma H, Mamouni J, Mansilla S, Mauk MG, Mirzaie-Joniani H, Mulhall HJ, Nevill JT, Parkin DM, Reddy AC, Remmerbach TW, Skoda C, Ts’ao C, Weigum SE, Withrow KP, Young EW, Ziober BL   +27 more
core   +2 more sources

Granulocyte-activating mediators (GRAM) [PDF]

, 1988
In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A., Möller, A., Putz, Reinhard, Zeck-Kapp, G.   +3 more
core   +1 more source

Fully Integrated Biochip Platforms for Advanced Healthcare [PDF]

, 2012
Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers.
Baj-Rossi, Camilla, Burleson, Wayne, Carrara, Sandro, Cavallini, Andrea, de Beeck, Maaike Op, Dehollain, Catherine, Ghoreishizadeh, Sara, Guiseppi-Elie, Anthony, Micheli, Giovanni De, Moussy, Francis Gabriel, Olivo, Jacopo, Taurino, Irene   +11 more
core   +5 more sources

Oxidative and apoptotic effects of fluoxetine and its metabolite norfluoxetine in Daphnia magna

Arhiv za Higijenu Rada i Toksikologiju, 2020
The aim of this study was to investigate the oxidative and apoptotic potential of fluoxetine, a widely used antidepressant in Turkey and the world, and of its metabolite norfluoxetine on a model non-target organism, Daphnia magna to see how exposure to ...
Över Sevgi Başalan, Güven Celal, Taskin Eylem, Sevgiler Yusuf   +3 more
doaj   +1 more source

TcI isolates of Trypanosoma cruzi exploit the antioxidant network for enhanced intracellular survival in macrophages and virulence in mice [PDF]

, 2016
Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL),
Basombrío, Miguel Ángel Manuel, Dhiman, Monisha, Garg, Nisha J., Hosakote, Yashoda M., Koo, Sue Jie, Parodi­ Talice, Adriana, Piñeyro, María Dolores, Robello, Carlos, Zago, María Paola   +8 more
core   +2 more sources

Crystalline Cytochrome c Peroxidase. [PDF]

Acta Chemica Scandinavica, 1966
Nils Ellfolk, O. B. Jørgensen, Guri Haustveit, L. A. Kristiansen, J. Brunvoll, E. Bunnenberg, Carl Djerassi, Ruth Records   +7 more
openaire   +2 more sources