Results 101 to 110 of about 10,403 (155)

Advancing inclusive healthcare through PBPK modelling: predicting the impact of CYP genotypes and enzyme ontogenies on infant exposures of venlafaxine and its active metabolite O-desmethylvenlafaxine in lactation. [PDF]

J Pharmacokinet Pharmacodyn
Pan X, Rowland Yeo K.
europepmc   +1 more source

Development and Characterization of pFluor50, a Fluorogenic-Based Kinetic Assay System for High-Throughput Inhibition Screening and Characterization of Time-Dependent Inhibition and Inhibition Type for Six Human CYPs. [PDF]

Molecules
Shriwas P, Revnew A, Roo S, Bender A, Miller K, Hadad CM, Lane TR, Ekins S, McElroy CA.   +8 more
europepmc   +1 more source

Effect of CYP2D6 and ABCB1 polymorphisms on pharmacokinetics and efficacy of aripiprazole in pediatric tic disorders. [PDF]

BMC Pediatr
Xin Y, Gao L, Li S, Wang J, Chen C, Tuo Y, Nie G, Li R, Sun D, Fu Y, Wang Y, Liu Z.   +11 more
europepmc   +1 more source

A Comprehensive Analysis Examining the Role of Genetic Influences on Psychotropic Medication Response in Children. [PDF]

Genes (Basel)
Singh J, Manginas A, Wilkins G, Santosh P.   +3 more
europepmc   +1 more source

Enhancing CYP2D6 genotyping with nanopore sequencing to address allele diversity P. vivax malaria elimination. [PDF]

Sci Rep
Wongsurawat T, Jenjaroenpun P, Suwannasin K, Wankaew N, Sanguansakpakdee N, Amornpornviwat T, Dondorp AM, Day NPJ, Nosten F, White NJ, Imwong M.   +10 more
europepmc   +1 more source

Impact of CYP2D6 genotype on fluoxetine exposure and treatment switch in adults and children/adolescents. [PDF]

Eur J Clin Pharmacol
Nordby KL, Faraj P, Molden E, Hole K.
europepmc   +1 more source

Epigenetics in pharmacogenes encoding metabolizing enzymes of second-generation antipsychotics used in schizophrenia and its clinical implications. [PDF]

Front Pharmacol
Alvarado AT, Zavaleta AI, Li-Amenero C, Bendezú MR, Garcia JA, Chávez H, Palomino-Jhong JJ, Surco-Laos F, Laos-Anchante D, Melgar-Merino EJ, Bolarte-Arteaga M, Tasayco-Yataco N, Pariona-Llanos R.   +12 more
europepmc   +1 more source

New cathinone-derived designer drugs 3-bromomethcathinone and 3-fluoromethcathinone : studies on their metabolism in rat urine and human liver microsomes using GC-MS and LC-high-resolution MS and their detectability in urine [PDF]

, 2012
Vollmar, Christian
core   +1 more source

Mono-CYP CHO Model: A Recombinant Chinese Hamster Ovary Cell Platform for Investigating CYP-Specific Tamoxifen Metabolism. [PDF]

Int J Mol Sci
Schulz C, Stegen S, Jung F, Küpper JH.
europepmc   +1 more source

Proof of principle concept for the analysis and functional prediction of rare genetic variants in the CYP2C19 and CYP2D6 genes. [PDF]

Hum Genomics
Johansson I, Lu Y, Zhou Y, Krebs K, Akcan M, Milani L, Ingelman-Sundberg M.   +6 more
europepmc   +1 more source