Results 81 to 90 of about 10,403 (155)

The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo

Drug Design, Development and Therapy, 2018
Dmitrij A Sychev,1 Ghulam Md Ashraf,2 Andrey A Svistunov,3 Maksim L Maksimov,4 Vadim V Tarasov,3 Vladimir N Chubarev,3 Vitalij A Otdelenov,1 Natal’ja P Denisenko,1 George E Barreto,5,6 Gjumrakch Aliev7–9 1Russian Medical Academy of ...
Sychev DA, Ashraf GM, Svistunov AA, Maksimov ML, Tarasov VV, Chubarev VN, Otdelenov VA, Denisenko NP, Barreto GE, Aliev G   +9 more
doaj  

Personalized medicine : the impact on chemistry [PDF]

, 2010
An effective strategy for personalized medicine requires a major conceptual change in the development and application of therapeutics. In this article, we argue that further advances in this field should be made with reference to another conceptual shift,
Marsh, Andrew, Singer, Donald R. J., Taylor, Paul C., Watkins, John   +3 more
core   +1 more source

Genetic polymorphism and drug interactions: their importance in the treatment of pain [PDF]

, 2018
Résumé: Objectif: Evaluer ľimpact de certains polymorphismes génétiques sur la variabilité de réponse aux analgésiques. Sources: Revue systématique par recherche informatisée structurée dans la base Medline (1966-2004), mots clés : pharmacogénétique ...
Dayer, Pierre, Desmeules, Jules, Piguet, Valérie, Samer, Caroline   +3 more
core  

Poster Sessions

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

Клинические аспекты функционирования системы цитохрома Р-450 микросом печени [PDF]

, 2005
В настоящем обзоре обобщены современные представления о системе цитохрома Р-450, роли в организме его важнейших изоформ, обсуждается вызванная лекарственными соединениями индукция либо ингибирование этой системы, приведены важные для клиники ...
Падалко, В.И., Севастьянова, Т.В.   +1 more
core  

Publication Only

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

Influence of tobacco smoke on the pharmacokinetics of citalopram and its enantiomers [PDF]

, 2012
The purpose of this study was to evaluate the influence of tobacco smoke on the pharmacokinetics of citalopram (CIT) and desmethylcitalopram (DCIT) and its enantiomers on an animal model.
Florek, Ewa, Jawień, Wojciech, Kulza, Maksymilian, Majcherczyk, Jagoda, Piekoszewski, Wojciech, Seńczuk-Przybyłowska, Monika   +5 more
core  

Duloksetins betydning for serumkonsentrasjonen av psykofarmaka som omsettes via CYP2D6 [PDF]

, 2009
Bakgrunn: Duloksetin er et relativt nytt antidepressivum som hemmer reopptak av serotonin og noradrenalin intersynaptisk. Det metaboliseres via Cytokrom P450 2D6 (CYP2D6) og CYP1A2, men antas også å være en svak/moderat hemmer av CYP2D6.
Enoksen, Torill Bakko
core  

Pharmakogenetik in der Rechtsmedizin [PDF]

, 2018
Zusammenfassung: Die Pharmakogenetik beschäftigt sich mit den genetisch bedingten Unterschieden bei der Arzneimittel-, Drogen oder Giftwirkung und ist somit auch für die rechtsmedizinische Begutachtung von Bedeutung.
Krämer, T.
core  

Cytochrome P450 enzyme mediated herbal drug interactions (Part 1) [PDF]

, 2014
It is well recognized that herbal supplements or herbal medicines are now commonly used. As many patients taking prescription medications are concomitantly using herbal supplements, there is considerable risk for adverse herbal drug interactions.
Prachayasittikul, Virapong, Wanwimolruk, Sompon   +1 more
core