Results 101 to 110 of about 104,306 (283)

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, EarlyView.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source

The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer [PDF]

, 2014
Peer reviewedPublisher ...
Alnabulsi, Ayham, Blihoghe, Daniela, Brown, Gordon T, Cash, Beatriz Giminez, Johansson, Petronella, Murray, Graeme I   +5 more
core   +3 more sources

Integrated and closed‐loop biorefinery strategies for efficient waste valorization and biofuel production

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Advancements in biofuel production technologies are essential for reducing global dependence on fossil fuels and addressing their overexploitation. Many valuable components of biomass, such as cellulose, hemicellulose, and lignin, remain underused in traditional biorefineries, which typically rely on a single feedstock to produce a primary ...
Marcos Paulo Patta Granado, Prakhar Talwar, Sahil Sahil, Andrea Cressoni De Conti, Sonil Nanda, Janusz A. Kozinski   +5 more
wiley   +1 more source

Therapeutic Drug Monitoring of Rivastigmine and Donepezil Under Consideration of CYP2D6 Genotype-Dependent Metabolism of Donepezil

Drug Design, Development and Therapy, 2020
Marion Ortner,1 Marion Stange,1 Heike Schneider,1 Charlotte Schröder,2 Katharina Buerger,3 Claudia Müller,3 Felix Müller-Sarnowski,1 Janine Diehl-Schmid,1 Hans Förstl,1 Timo Grimmer1 ,* Werner Steimer2, * 1Department of Psychiatry and
Ortner M, Stange M, Schneider H, Schröder C, Buerger K, Müller C, Müller-Sarnowski F, Diehl-Schmid J, Förstl H, Grimmer T, Steimer W   +10 more
doaj  

Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.
Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger, Elric Zweck, Constanze Moos, Patrick Horn, Fabian Voß, Heinz‐Peter Schultheiss, Jacob Eifer Møller, Udo Boeken, Hug Aubin, Artur Lichtenberg, Malte Kelm, Michael Roden, Amin Polzin, Ralf Westenfeld, Julia Szendroedi, Daniel Scheiber   +15 more
wiley   +1 more source

CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma. [PDF]

, 2015
BackgroundCytochrome P450 1B1 (CYP1B1) has been shown to be up-regulated in many types of cancer including renal cell carcinoma (RCC). Several reports have shown that CYP1B1 can influence the regulation of tumor development; however, its role in RCC has ...
Arichi, Naoko, Chang, Inik, Dahiya, Rajvir, Deng, Guoren, Fukuhara, Shinichiro, Hiraki, Miho, Hirata, Hiroshi, Majid, Shahana, Mitsui, Yozo, Shahryari, Varahram, Shiina, Hiroaki, Tanaka, Yuichiro, Wong, Darryn K, Yamamura, Soichiro, Yasumoto, Hiroaki   +14 more
core   +2 more sources

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Polymorphism of xenobiotic biotransformation enzyme genes and their role in early pregnancy loss

Фундаментальная и клиническая медицина
Considering the progressive decrease in the number of women of fertile age, as well as children and adolescents, the primary medical and social task at the present stage is to preserve the reproductive health and life of women, preserving every desired ...
S. V. Matoshin, S. V. Shramko
doaj   +1 more source

Fully Integrated Biochip Platforms for Advanced Healthcare [PDF]

, 2012
Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers.
Baj-Rossi, Camilla, Burleson, Wayne, Carrara, Sandro, Cavallini, Andrea, de Beeck, Maaike Op, Dehollain, Catherine, Ghoreishizadeh, Sara, Guiseppi-Elie, Anthony, Micheli, Giovanni De, Moussy, Francis Gabriel, Olivo, Jacopo, Taurino, Irene   +11 more
core   +5 more sources

Integrated Anatomical, Chemical, Biological and Computational Studies Approach of Myrcia sylvatica (G. Mey) DC. A Multifaceted Insight Into a Promising Amazonian Species

Flavour and Fragrance Journal, EarlyView.
This study presents an integrated anatomical, chemical, biological, and computational analysis of Myrcia sylvatica, revealing key bioactive compounds with antioxidant and toxicological potential, and identifying spathulenol and globulol as promising acetylcholinesterase inhibitors with favourable pharmacokinetic properties. ABSTRACT Myrcia sylvatica (G.
Eliza de Jesus Barros dos Santos, Zelina Ataíde Correia, Ely Simone Cajueiro Gurgel, Leonardo Souza da Costa, Mabrouk Horchani, Hayet Edziri, Ravendra Kumar, Anderson de Santana Botelho, Karyme do Socorro de Souza Vilhena, Eloisa Helena de Aguiar Andrade, Mozaniel Santana de Oliveira   +10 more
wiley   +1 more source