Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu +8 more
wiley +1 more source
Candidate-gene-based study of CYP3A-related single-nucleotide polymorphisms using 4β-hydroxycholesterol/cholesterol ratio as biomarker in a Japanese cohort. [PDF]
Tanaka R +14 more
europepmc +1 more source
Prostate Cancer Development, Progression, and Therapy
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin +9 more
wiley +1 more source
Drug Interactions of Vebreltinib, a Novel Type I c-Met Inhibitor, Coadministration With Rifampin or Itraconazole in Healthy Participants. [PDF]
Chen J +15 more
europepmc +1 more source
Uptake, metabolism, and bioremediation of neonicotinoid insecticides in soil–plant systems: A review
This review summarizes the uptake and metabolic transformation of neonicotinoid insecticides in plants, showing that some metabolites exhibit higher toxicity. We also critically assess promising bioremediation strategies using microbes and plant–microbe interactions to reduce residue contamination.
Wenwen Guo +5 more
wiley +1 more source
Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers. [PDF]
Tuloup V, Tod M, Bourguignon L.
europepmc +1 more source
The near‐T2T genome assembly of Erigeron sumatrensis reveals an allohexaploid origin, evolution, and the interaction between the herbicidal target of the HPPD family and mesotrione. Abstract Species of Erigeron, members of the family Asteraceae, have invaded and adapted to agricultural fields and uncultivated habitats worldwide. Erigeron sumatrensis is
Yingying Wang +8 more
wiley +1 more source
Clinical relevance of cytochrome P450-mediated drug-drug interactions in hospitalised older adults: implications for community pharmacy. [PDF]
Lozano R, Bona C.
europepmc +1 more source
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova +10 more
wiley +1 more source
Xenobiotic Metabolizing Enzyme Response of Rainbow Trout (Oncorhynchus mykiss) to Benzophenone-3 and N,N-diethyl-m-toluamide. [PDF]
Bozcaarmutlu-Büken A +4 more
europepmc +1 more source

