Results 61 to 70 of about 42,048 (270)

The preparation and characterisation of novel microperoxidase biocatalysts [PDF]

open access: yes, 1987
Microperoxidases are haem oligopeptides, derived from the proteolytic digestion of cytochrome c, possessing peroxidase activity. They are termed "microperoxidases" in contrast to other relatively large peroxidases such as horseradish peroxidase.
Atkinson, Susan Lesley
core  

Bisphenol Analog‐Induced Cytotoxicity: Unraveling Endoplasmic Reticulum (ER) Stress and Apoptotic Pathways

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is increasingly replaced by structural analogs, yet their safety remains insufficiently characterized. This study investigated whether BPA and selected analogs, bisphenol AF (BPAF), bisphenol AP (BPAP), bisphenol P (BPP), and bisphenol E (BPE), induce cytotoxicity through activation of endoplasmic reticulum (ER) stress and ...
Rafia Afroze Rifa, Ramon Lavado
wiley   +1 more source

A study of cytochrome P-450 from Saccharomyces cerevisiae.

open access: yes, 1979
Yeast (Saccharomyces cerevisiae NCYC No. 240) will synthesise a cytochrome P-450, with the characteristic spectral peak at 450 nm, in reduced form in complex with carbon monoxide.
Gondal, Javed Anwar.
core  

Properties of NADPH-cytochrome P-450 reductase purified from rabbit liver microsomes [PDF]

open access: yes, 1979
NADPH-cytochrome P-450 reductase has been purified to electrophoretic homogeneity from rabbit liver microsomes by a procedure that may be used in conjunction with the isolation of the major forms of cytochrome P-450. The purified reductase is active in a
Coon, Minor J., French, John S.
core   +1 more source

Parental Exposure to Nanoplastics and Graphene Oxide Induces Transgenerational Toxicity in Caenorhabditis elegans

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Environmental pollution by emerging contaminants such as nanoplastics (NPs) and graphene oxide (GO) represents a growing threat to global health and ecosystems. This study investigated the effects of parental exposure, both isolated and combined, to 100 μg/L NPs (polystyrene, spherical, 100 nm) and 100 mg/L GO, using Caenorhabditis elegans as ...
Gabriela Corrêa Soares   +6 more
wiley   +1 more source

The effect of variation of dose, time toward cauli flower (Brassica oleracea var BotrytisL.) On hepatic cytochrome P-450 level rats given theophylline

open access: yes, 2011
Cytochrome  P-450  as  a  major  component  enzyme  system  in  drug metabolism. Activity  enzyme  of  cytochrome  P-450  was  influenced  by  internal and external factors.
., Sumantri; Faculty of Pharmacy, Universitas Gadjah Mada. Yogyakarta, Indonesia   +3 more
core   +1 more source

Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: Lipid requirement for drug demethylation [PDF]

open access: yes, 1969
A solubilized hepatic microsomal enzyme system previously shown to catalyze the [omega]-hydroxylation of fatty acids also catalyzes the hydroxylation of drugs. Benzphetamine, aminopyrine, ethylmorphine, hexobarbital, norcodeine, and -nitroanisole undergo
Strobel, Henry W.   +2 more
core   +1 more source

Hybrid Quatsome‐Encapsulated Silver Nanoparticles as Stable Plasmonic Substrates for Surface‐Enhanced Raman Scattering

open access: yesJournal of Raman Spectroscopy, EarlyView.
In this work, silver nanoparticles encapsulated within quatsome membranes have shown to preserve their plasmonic properties for at least 165 days without aggregation. These hybrid nanostructures enable strong SERS enhancement of pyrene and Prodan by confining the molecules within a few nanometers from the silver surface.
Renato Cezar Peramezza Ribeiro   +10 more
wiley   +1 more source

Studies on native and reconstituted FMN-depleted NADPH-cytochrome P-450 reductase

open access: yes, 1987
The research on flavins and flavoproteins started in 1879 with the discovery of the yellow pigment "lactochrome" in whey by Blyth. Later it turned out that "lactochrome" and other isolated yellow pigments were derivatives of riboflavin (vitamin B2).
Bonants, P., Bonants, P.J.M.
core  

Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh   +3 more
wiley   +1 more source

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