Results 101 to 110 of about 300,993 (238)

Defining Resonance Raman Spectral Responses to Substrate Binding by Cytochrome P450 from \u3cem\u3ePseudomonas putida\u3c/em\u3e [PDF]

open access: yes, 2008
Resonance Raman spectra are reported for substrate-free and camphor-bound cytochrome P450cam and its isotopically labeled analogues that have been reconstituted with protoheme derivatives that bear -CD3 groups at the 1, 3, 5, and 8-positions (d12 ...
Deng, Tianjing   +5 more
core   +1 more source

Acetaminophen detoxification in cucumber plants via induction of glutathione S-transferases. [PDF]

open access: yes, 2019
Many pharmaceutical and personal care products (PPCPs) enter agroecosystems during reuse of treated wastewater and biosolids, presenting potential impacts on plant development.
Dudley, Stacia   +4 more
core  

A single meal has the potential to alter brain oxylipin content. [PDF]

open access: yes, 2020
Our objective was to determine whether consumption of a single meal has the potential to alter brain oxylipin content. We examined the cerebrum of mice fed a single high-fat/high-sucrose Western meal or a low-fat/low-sucrose control meal, as well as ...
Aung, HH   +5 more
core   +1 more source

Pharmacological regulation of the activity of cytochrome P450 3A4 AND P450 2C9 isoenzymes by vitamins and natural compounds

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The influence of vitamins with antioxidant properties (vitamins A, E, C), B vitamins (B1, B2, B6) and vitamin-like substances (coenzyme Q10, taurine and L-carnitine) on the enzymes of the first phase of xenobiotic metabolism - cytochromes P450 3A4 and ...
E. V. Shikh   +3 more
doaj  

Fluorescencein situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1 [PDF]

open access: bronze, 1994
Kiyoshi Inoue   +6 more
openalex   +1 more source

The nitrite anion: the key intermediate in alkyl nitrates degradative mechanism. [PDF]

open access: yes, 2007
Alkyl nitrates, _in vivo_, are metabolized to yield nitric oxide, and thiol groups are considered necessary cofactors. This statement is based on studies that underline how these species potentiate hemodynamic responsiveness to nitrates in patients with ...
Loris Grossi
core   +1 more source

Tuning architectural organization of eukaryotic P450 system to boost bioproduction in Escherichia coli

open access: yesNature Communications
Eukaryotic cytochrome P450 enzymes, generally colocalizing with their redox partner cytochrome P450 reductase (CPR) on the cytoplasmic surface of organelle membranes, often perform poorly in prokaryotic cells, whether expressed with CPR as a tandem ...
Yikui Li   +7 more
doaj   +1 more source

Resonance Raman Characterization of the Peroxo and Hydroperoxo Intermediates in Cytochrome P450 [PDF]

open access: yes, 2008
Resonance Raman (RR) studies of intermediates generated by cryoreduction of the oxyferrous complex of the D251N mutant of cytochrome P450cam (CYP101) are reported.
Denisov, Ilia G.   +4 more
core   +1 more source

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