Results 51 to 60 of about 300,993 (238)

Osteomalacia in an HIV-infected man receiving rifabutin, a cytochrome P450 enzyme inducer: a case report

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2008
Introduction People infected with human immunodeficiency virus are frequently treated with medications that can induce or inhibit cytochrome P450 enzymes.
Horne Anne M   +3 more
doaj   +1 more source

P450BM3-Catalyzed Oxidations Employing Dual Functional Small Molecules [PDF]

open access: yes, 2019
A set of dual functional small molecules (DFSMs) containing different amino acids has been synthesized and employed together with three different variants of the cytochrome P450 monooxygenase P450BM3 from Bacillus megaterium in H2O2-dependent oxidation
Girhard, Marco   +5 more
core   +1 more source

Cytochrome P450 flexibility [PDF]

open access: yesProceedings of the National Academy of Sciences, 2003
Cytochrome P450 refers to a group of enzymes that catalyze the monooxygenation of various organic molecules in the following reaction: \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \setlength{\oddsidemargin}{-69pt} \begin{document} \begin ...
openaire   +3 more sources

Comprehensive mRNA and microRNA analysis revealed the effect and response strategy of freshwater fish, grass carp (Ctenopharyngodon idella) under geosmin exposure

open access: yesEcotoxicology and Environmental Safety
Geosmin is an environmental pollutant that causes off-flavor in water and aquatic products. The high occurrence of geosmin contamination in aquatic systems and aquaculture raises public awareness, however, few studies have investigated the response ...
Jun-ming Zhang   +9 more
doaj   +1 more source

Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11 [PDF]

open access: yes, 2009
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Eiichi Akaho   +3 more
core   +1 more source

Heterologous caffeic acid biosynthesis in Escherichia coli is affected by choice of tyrosine ammonia lyase and redox partners for bacterial Cytochrome P450

open access: yesMicrobial Cell Factories, 2020
Background Caffeic acid is industrially recognized for its antioxidant activity and therefore its potential to be used as an anti-inflammatory, anticancer, antiviral, antidiabetic and antidepressive agent.
Kristina Haslinger   +1 more
doaj   +1 more source

Functional characterization of the cytochrome P450 monooxygenase CYP71AU87 indicates a role in marrubiin biosynthesis in the medicinal plant Marrubium vulgare. [PDF]

open access: yes, 2019
BackgroundHorehound (Marrubium vulgare) is a medicinal plant whose signature bioactive compounds, marrubiin and related furanoid diterpenoid lactones, have potential applications for the treatment of cardiovascular diseases and type II diabetes.
Addison, J Bennett   +5 more
core   +6 more sources

Insecticide induction of O-demethylase activity and expression of cytochrome P450 genes in the red imported fire ant (Solenopsis invicta Buren)

open access: yesJournal of Integrative Agriculture, 2016
The red imported fire ant (Solenopsis invicta) is a global major invasive pest, and has caused significant economic, social and environmental impacts since its invasion to mainland of China in 2004.
Bai-zhong ZHANG   +5 more
doaj   +1 more source

Cytochrome P450 monooxygenases

open access: yesCurrent Opinion in Chemical Biology, 1998
The field of P450 research is progressing rapidly. The active sites of structurally characterized bacterial P450 enzymes have been rationally re-engineered to alter both substrate specificity and selectivity of substrate oxidation. Many human P450 enzymes have been functionally expressed and new methods of substrate turnover described.
openaire   +3 more sources

Genome-wide identification and transcriptomic data exploring of the cytochrome P450 family in Chinese cabbage (Brassica rapa L. ssp. pekinensis)

open access: yesJournal of Plant Interactions, 2021
Cytochrome P450 genes are involved in the catalysis of various reactions, including growth, development and secondary metabolite biosynthetic pathways.
Shu Zhang   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy