Results 121 to 130 of about 174,785 (211)

Preventing Carcinogenesis with Compounds that Inhibit Cytochrome P450 1A1 and 1B1

Biochemistry & Physiology: Open Access, 2018
Cytochrome P450 1A1 and 1B1 convert polycyclic aromatic hydrocarbons to carcinogenic compounds in extrahepatic tissues. In 1997, resveratrol, a naturally occurring stilbene found in grapes and red wine, was found to inhibit the growth of tumors and that one potential mechanism was by inhibiting cytochrome P450 1A1 and 1B1.
openaire   +1 more source

Study of Cytochrome P450 1A1 (T3801C) Single Nucleotide Polymorphism in Patients with Breast Cancer in Mazandaran Province-Northern Iran

Research in Molecular Medicine, 2015
 Background: Breast cancer is the first leading cause of cancer-related death in women. Pesticides which are excessively used in northern Iran are one of the most important risk factors for breast cancer incidence.
Ghazaleh Khalili, Ali Barzegar, Novin Nikbakhsh, Zarbakht Ansari-Pirsaraee   +3 more
doaj  

Genetic Polymorphisms of the Human Cytochrome P450 1A1 (CYP1A1) and Cervical Cancer Susceptibility among Northeast Thai Women. [PDF]

Asian Pac J Cancer Prev, 2020
Wongpratate M, Ishida W, Phuthong S, Natphopsuk S, Ishida T.   +4 more
europepmc   +1 more source

The role of dolutegravir in the management of HIV infections

Infection and Drug Resistance, 2015
Misty M Miller,1 Michelle D Liedtke,1 Staci M Lockhart,2 R Chris Rathbun1 1Department of Pharmacy: Clinical and Administrative Sciences, University of Oklahoma College of Pharmacy, Oklahoma City, OK, USA; 2AbbVie Inc., Oklahoma City, OK, USA Abstract ...
Miller MM, Liedtke MD, Lockhart SM, Rathbun RC   +3 more
doaj  

Long-term efficacy and safety of raltegravir in the management of HIV infection

Infection and Drug Resistance, 2014
Michelle D Liedtke, C Ryan Tomlin, Staci M Lockhart, Misty M Miller, R Chris Rathbun Department of Clinical and Administrative Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA Abstract: Raltegravir is ...
Liedtke MD, Tomlin CR, Lockhart SM, Miller MM, Rathbun RC   +4 more
doaj  

Activation of the Aryl Hydrocarbon Receptor-Cytochrome P450 1A1 Axis Mediates the Selective Cytotoxicity of 2‑Phenyl-Imidazo[1,2‑<i>a</i>]Pyridine Derivatives in Triple-Negative Breast Cancer Cells. [PDF]

ACS Pharmacol Transl Sci
Lin LW, Beeman CE, Yang J, Ebrahimi A, Büchel S, Grathwol CW, Jung N, Bräse S, Hendrix DA, Maier CS, Cato ACB, Kolluri SK.   +11 more
europepmc   +1 more source

Epigenetic mechanisms mediate cytochrome P450 1A1 expression and lung endothelial injury caused by MRSA in vitro and in vivo. [PDF]

FASEB J
Ha AW, Meliton LN, Chen W, Wang L, Maienschein-Cline M, Jacobson JR, Letsiou E, Dudek SM.   +7 more
europepmc   +1 more source

Establishment and characterization of cytochrome P450 1A1 CRISPR/Cas9 Knockout Bovine Foetal Hepatocyte Cell Line (BFH12). [PDF]

Cell Biol Toxicol
Iori S, D'Onofrio C, Laham-Karam N, Mushimiyimana I, Lucatello L, Lopparelli RM, Gelain ME, Capolongo F, Pauletto M, Dacasto M, Giantin M.   +10 more
europepmc   +1 more source

Mulberry leaf supplementation inhibits skatole deposition by regulating gut microbiota and upregulating liver cytochrome P450 1A1 expression in finishing pigs. [PDF]

Anim Nutr
Sun Y, Men X, Lin T, Deng B, Zhong S, Huo J, Qin K, Lv Z, Xu Z, Li Y.   +9 more
europepmc   +1 more source

Cytochrome P450 1A1 gene polymorphisms and cervical cancer risk: A systematic review and meta-analysis. [PDF]

Medicine (Baltimore), 2018
Ding B, Sun W, Han S, Cai Y, Ren M, Shen Y.   +5 more
europepmc   +1 more source