Results 161 to 170 of about 102,161 (305)

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan   +5 more
wiley   +1 more source

Communicative Nanomotors Reprogram Cancer Cell Death via Pyroptosis

open access: yesAngewandte Chemie, EarlyView.
Communicative nanomotors respond to elevated ROS in the tumor microenvironment, enabling active communication and selective mitochondrial targeting through non‐covalent surface engineering. Their precise interaction with cells induces mitochondrial damage, cytochrome c release, and pyroptotic cell death, while chemotactic motility ensures deeper tumor ...
Mingchen Sun   +3 more
wiley   +2 more sources

The Splitting with Silver Salts of the Cysteine-porphyrin Bonds in Cytochrome c. [PDF]

open access: bronze, 1950
Karl-Gustav Paul   +3 more
openalex   +1 more source

Harnessing the multidimensional bioactivity of Chaetomorpha aerea: Integrative phytochemical profiling with in vitro, in vivo, and in silico insights

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study revealed the antioxidant, anti‐inflammatory, and antidiabetic potentials of the seaweed Chaetomortpha aerea using in vitro, in vivo, and in silico approaches along with phytochemical analysis using gas chromatography–mass spectrometry. ADME/T analysis was also carried out to confirm drug likeness and toxicity prediction.
Md. Mahmudul Hasan   +7 more
wiley   +1 more source

The Iron–Sulfur Cluster of Bacterioferritin‐Associated Ferredoxin (Bfd): a “Biological Fuse” that Prevents Oxidative Damage to Cells?

open access: yesAngewandte Chemie, EarlyView.
When cellular iron is low, bacterioferritin (Bfr) releases its stored iron through a reductive process dependent on the [2Fe–2S] ferredoxin Bfd. Why accessing stored iron should depend on an iron‐requiring protein when iron is scarce is unclear. Here, we show that the Bfd [2Fe–2S] cluster is sensitive to oxidative stress, suggesting that it may act as ...
Justin M. Bradley   +4 more
wiley   +2 more sources

Endogenously Triggered DNAzyme‐Based Nanostructures for Gene‐Combined Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
DNAzymes show great promise for gene regulation and therapeutic use via controlled release triggered by endogenous factors. This review summarizes recent advances in designing and constructing nanoscale platforms enabling endogenously triggered release of DNAzyme.
Theoneste Muyizere   +4 more
wiley   +1 more source

Embracing Complexity: Peptides as Tunable Scaffolds in the Construction of Discrete Supramolecular Systems

open access: yesAngewandte Chemie, EarlyView.
The inherent chirality, tunability, biocompatibility, and robustness of peptides provide an exciting opportunity for supramolecular chemistry. In this mini‐review, we explore uses of peptides in discrete supramolecular systems, how chemists can draw inspiration from larger biological assemblies, and discuss how embracing the complexity of peptide ...
Ben E. Barber   +3 more
wiley   +2 more sources

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