Results 171 to 180 of about 353,099 (395)
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
Cytochrome C6 of Chlamydomonas Reinhardtii - A Heme Protein with Unusual Properties [PDF]
Nicole Lynn Vanderbush +3 more
openalex +1 more source
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han +16 more
wiley +1 more source
Analysis of the Structural and Functional Role of the Dicyclohexylcarbodiimide (DCCD) Binding Site (E90-H212-Y246) in Subunit III of Bovine Heart and Rhodobacter Sphaeroides Cytochrome c Oxidase using Mutagenesis and Chemical Modification [PDF]
Lawrence J. Prochaska +6 more
openalex +1 more source
Human cytochromes P450 in health and disease
D. Nebert, K. Wikvall, W. Miller
semanticscholar +1 more source
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos +12 more
wiley +1 more source
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu +6 more
wiley +1 more source

