Results 141 to 150 of about 18,948,758 (389)
Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Characterization of cytochrome‐c oxidase mutants in human fibroblasts [PDF]
, 1988 D. Moira Glerum +3 more
openalex +1 more source
Advanced Science, EarlyView.Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang +8 more
wiley +1 more source
Resonance Raman Characterization of the Peroxo and Hydroperoxo Intermediates in Cytochrome P450 [PDF]
, 2008 Resonance Raman (RR) studies of intermediates generated by cryoreduction of the oxyferrous complex of the D251N mutant of cytochrome P450cam (CYP101) are reported.
Denisov, Ilia G. +4 more
core +1 more source
Advanced Science, EarlyView.This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang +12 more
wiley +1 more source
Specificity of Small c‑Type Cytochromes in Anaerobic Ammonium Oxidation
ACS Omega, 2021 Mohd. Akram +3 more
doaj +1 more source
Immunological similarity of the NADH—cytochrome c electron transport system in microsomes, Golgi complex and mitochondrial outer membrane of rat liver cells [PDF]
, 1976 Nica Borgese, Jacopo Meldolesi
openalex +1 more source
Advanced Science, EarlyView.Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu +20 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that actin remodeling regulates mitochondrial elongation as a defense strategy in plants. Flagellin perception induces fusion‐dependent elongation, supported by cortical actin bundles, to repair damage and boost ATP and ROS production.
Junxiu Hou +5 more
wiley +1 more source
Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition
, 2018 Carlos A. Elena‐Real +8 more
openalex +1 more source