Results 91 to 100 of about 9,325 (207)

CyTOF as a suitable tool for stratification and monitoring of cancer patients

Journal of Translational Medicine
Abstract Despite the recent implementation of immunotherapies into clinical practice of various tumor types, the immunobiology of tumors and in particular the role and clinical relevance of the different immune cell populations and their function still remained unclear.
Barbara Seliger, Chiara Massa
openaire   +3 more sources

Evaluation of Methods for Identifying Human Monocytes by Flow Cytometry: TLR2 May be an Optimal Marker

Immunology, EarlyView.
Monocytes play crucial roles in the pathobiology of a wide range of medical conditions, including infection, autoimmunity, cardiovascular disease and malignancies. Studies using flow cytometry revealed the complexity of monocyte biology, including the identification of three human monocyte subsets: classical (CD14pos CD16neg), intermediate (CD14pos ...
Mie Wolff Kristensen, Katrine Skjøt Harbo, Thomas Vorup‐Jensen, Marianne Hokland, Morten Nørgaard Andersen   +4 more
wiley   +1 more source

Supplementary Table TS1 from Comprehensive Characterization of the Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis

, 2022
supplementary table 1 shows cell type annotation markers, clinical information of patients, cross-technique comparison of cell subset abundance and expression of cell type marker genes in CITE-seq and ...
Beena E. Thomas (7534454), Michael C. Wendl (15131822), Emilie Anderson (15131819), Ioannis S. Vlachos (12916754), Daniel Auclair (15122724), Mark A. Fiala (15032471), Brian H. Lee (15131801), Swati S. Bhasin (15131804), Ying Li (15099645), Manoj K. Bhasin (15131837), Sacha Gnjatic (15020045), Li Ding (15061726), Edgar Gonzalez-Kozlova (13880301), Mark Hamilton (15131831), Hearn Jay Cho (9121966), Seunghee Kim-Schulze (39495), Shaji K. Kumar (15129447), Geoffrey Kelly (9119783), Adeeb H. Rahman (15122478), William Pilcher (15131807), Taxiarchis Kourelis (6757724), Yered Pita-Juarez (15131813), Ravi Vij (426701), Surendra Dasari (15054563), John F. DiPersio (15002214), Stephen T. Oh (15117676), Reyka G. Jayasinghe (15131798), Deon Bryant Doxie (15131810), Michael Strausbauch (15131816), Madhav V. Dhodapkar (15131834), Lijun Yao (8087129), David Avigan (14885192), Travis Dawson (15131825), Shaadi Mehr (825272), Darwin D'souza (15131828), Giulia Cheloni (15102444), Kavita M. Dhodapkar (15128388)   +36 more
core   +1 more source

Metal Isotope-Tagged Nanomaterials for Mass Cytometry and Imaging: Advances and Biomedical Applications

Nano Biomedicine and Engineering
Mass cytometry (cytometry by time-of-flight (CyTOF)) and imaging mass cytometry (IMC) are transformative technologies that combine flow cytometry principles with time-of-flight mass spectrometry (TOF-MS).
Dongling Jia, Minhui Cui, Weiwei Wang, Jielin Sun, Xiaoxiang Chen   +4 more
doaj   +1 more source

Multi‐Omics Insights Into Circulating T‐Cell Metabolic Reprogramming and Treg Dysfunction in Moyamoya Disease

MedComm, Volume 7, Issue 11, November 2026.
The comprehensive study design is illustrated. A multi‐omics approach was used to characterize T‐cell metabolic alterations in MMD. By integrating mass cytometry (CyTOF), single‐cell RNA sequencing (scRNA‐seq), bulk RNA‐seq, metabolomics, and flow cytometry, we aimed to elucidate metabolic reprogramming in circulating T cells and Treg dysfunction in ...
Zhiyao Zheng, Qiheng He, Xinyu Ma, Bojian Zhang, Junsheng Li, Chenglong Liu, Siqi Mou, Wei Sun, Xiangjun Shi, Wenjing Wang, Dong Zhang, Peicong Ge, Jizong Zhao   +12 more
wiley   +1 more source

Image_2_Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials.JPEG

, 2019
Flow cytometry is a widely applied approach for exploratory immune profiling and biomarker discovery in cancer and other diseases. However, flow cytometry is limited by the number of parameters that can be simultaneously analyzed, severely restricting ...
Sabelo Lukhele (3834571), Naoto Hirano (188272), Ben Wang (250897), Pam S. Ohashi (6710198), Marcus Butler (6457157), David G. Brooks (6710204), Cynthia J. Guidos (6710195), Bethany L. MacLeod (6710183), Albiruni R. Abdul Razak (4723662), Russell J. Dickson (6710186), Babak Noamani (461397), Tracy L. McGaha (6710192), Ramy Gadalla (3819166), Lillian L. Siu (6710201), Wenxi Xu (1517956), Heidi J. Elsaesser (6710189), Mengdi Guo (6457172)   +16 more
core   +1 more source

Cytokine-stimulated Phosphoflow of PBMC Using CyTOF Mass Cytometry

BIO-PROTOCOL, 2015
Phosphorylation of tyrosine, serine, and threonine residues is critical for the control of protein activity involved in various cellular events. An assortment of kinases and phosphatases regulate intracellular protein phosphorylation in many different cell signaling pathways.
Rosemary Fernandez, Holden Maecker
openaire   +3 more sources

Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types

Nature Communications, 2020
Immunotherapy has emerged as a promising approach to treat cancer, however, its efficacy in highly malignant brain-tumors, glioblastomas (GBM), is limited.
Jasneet Kaur Khalsa, Nina Cheng, Joshua Keegan, Ameen Chaudry, Joseph Driver, Wenya Linda Bi, James Lederer, Khalid Shah   +7 more
doaj   +1 more source

Quality control measurements of the murine single-cell CyTOF and transcriptomics dataset.

, 2023
(A) Representative flow cytometry analysis of the input and flowthrough for the removal of circulating CD45+ immune cells using magnetic sorting. (B) Identification of CD45+ cells in the CyTOF murine meninges dataset.
Lalit Kumar Dubey (5758280), Juan F. Quintana (8044493), Nono-Raymond Kuispond Swar (17420082), Gail McConnell (2180448), Michael Haley (7646750), Neil A. Mabbott (7361273), Luis de Lecea (711657), Annette MacLeod (12779), Matthew C. Sinton (11056182), Praveena Chandrasegaran (17420073), David Bending (17420085), Moumen Al Samman (17420079), John Ogunsola (17420076), Dieudonné Mumba Ngoyi (7889651)   +13 more
core   +1 more source

Single-cell Immune Atlas of Pituitary Neuroendocrine Tumors using CyTOF

Whether the tumor microenvironment (TME) is shaped by endocrine function, as well as its diversity and function, in pituitary neuroendocrine tumors (pitNETs) remains understudied.
Guo, Xiaopeng
core   +1 more source