Results 91 to 100 of about 1,677 (171)

Cardiopulmonary adaptations of a diving marine mammal, the bottlenose dolphin: Physiology during anesthesia

Physiological Reports, Volume 12, Issue 17, September 2024.
Abstract Diving marine mammals are a diverse group of semi‐ to completely aquatic species. Some species are targets of conservation and rehabilitation efforts; other populations are permanently housed under human care and may contribute to clinical and biomedical investigations.
Carolina R. Le‐Bert, Gordon S. Mitchell, Leah R. Reznikov   +2 more
wiley   +1 more source

Effect of cytoglobin overexpression on extracellular matrix component synthesis in human tenon fibroblasts

Biological Research, 2019
Background Conjunctival filtering bleb scar formation is the main reason for the failure of glaucoma filtration surgery. Cytoglobin (Cygb) has been reported to play an important role in extracellular matrix (ECM) remodeling, fibrosis and tissue damage ...
Haiying Wei, Lili Lin, Xiaomei Zhang, Zhuolei Feng, Yeqing Wang, Yan You, Xiaodan Wang, Yongsheng Hou   +7 more
doaj   +1 more source

A comprehensive review of specific activity and intrinsic connections of food‐derived bioactive peptides for human health

Food Frontiers, Volume 5, Issue 3, Page 1145-1165, May 2024.
This review provides an in‐depth exploration of nineteen types of food‐derived bioactive peptides, focusing on their intricate interplay and foundational functionalities, particularly antioxidant actions, in relation to human health. It emphasizes the complex yet crucial mechanisms of these peptides in various bodily systems and underscores the ...
Tiantian Zhao, Guowan Su, Lijun Zhang, Jieqiong Chen, Yehui Zhang, Weifeng Liu, Mouming Zhao, Jianan Zhang, Qingrong Huang   +8 more
wiley   +1 more source

Stimulation of Cytoglobin Expression and Improvement in ROS-Related Aging Markers in Skin Cells with Tropaeolum majus Extract

Cosmetics
Reactive oxygen species (ROS) and mitochondrial dysfunction play a major role in skin aging. Due to Tropaeolum majus’ suggested protective actions against ROS, a link between T.
Andrea Cipriano, Fang Qi, Karen Kai-Lin Hwang, Priscila Chiavellini, Wei-Chieh Mu, Elodie Aymard, Philippe Schaeffer, Marion Renault, Tanesha Naiken, Emmanuelle Leblanc, Jamila Dhiab, Brigitte Closs, Karl Pays, Delphine Sauce, David Furman, Vittorio Sebastiano, Knut Woltjen, Carine Nizard, Anne-Laure Bulteau   +18 more
doaj   +1 more source

Iron–histidine bonding in bishistidyl hemoproteins–A local vibrational mode study

Journal of Computational Chemistry, Volume 45, Issue 9, Page 574-588, April 5, 2024.
Using our local mode analysis, the strength of FeN distal and proximal bonds was investigated for bishistidyl proteins from bacteria, animals, human, and plants via local mode force constants ka(FeN). We also investigated the stiffness of the axial NFeN bond angle via local mode force constants ka(NFeN).
Marek Freindorf, Juliana J. Antonio, Elfi Kraka   +2 more
wiley   +1 more source

The effect of reactive oxygen and nitrogen species on the structure of cytoglobin: A potential tumor suppressor

Redox Biology, 2018
Many current anti-cancer therapies rely on increasing the intracellular reactive oxygen and nitrogen species (RONS) contents with the aim to induce irreparable damage, which subsequently results in tumor cell death.
Joey De Backer, Jamoliddin Razzokov, Dietmar Hammerschmid, Carl Mensch, Zainab Hafideddine, Naresh Kumar, Geert van Raemdonck, Maksudbek Yusupov, Sabine Van Doorslaer, Christian Johannessen, Frank Sobott, Annemie Bogaerts, Sylvia Dewilde   +12 more
doaj   +1 more source

Cytoglobin as a Marker of Hepatic Stellate Cell-derived Myofibroblasts

Frontiers in Physiology, 2015
Myofibroblasts play important roles in inflammation, fibrosis and tumorigenesis in chronically inflamed liver. Liver myofibroblasts originate from hepatic stellate cells, portal fibroblasts or mesothelial cells, and they are localized in and around ...
Norifumi eKawada
doaj   +1 more source

Cytoglobin expression of rectal subepithelial myofibroblasts: significant alterations of cytoglobin+ stromal cells in long-standing ulcerative colitis.

Histology and histopathology, 2011
Cytoglobin/stellate cell activation-associated protein (Cygb/STAP), a hemoprotein, functions as part of an O2 reservoir with protective effects against oxidative stress in hepatic stellate cells. Heterogeneous expression of the neural cell adhesion molecule (NCAM)+ and/or α-smooth muscle actin (αSMA)+ has been noted in subepithelial myofibroblasts and ...
Okayasu, Isao, Mikami, Tetuo, Yoshida, Tsutomu, Hana, Kiyomi, Yokozawa, Yokozawa, Sada, Miwa, Fujiwara, Mutsunori, Kawada, Norifumi   +7 more
openaire   +3 more sources

The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms

Journal of Hematology & Oncology, 2016
Background Neuroblastoma is a relatively common and highly belligerent childhood tumor with poor prognosis by current therapeutic approaches. A novel anti-cancer agent of the di-2-pyridylketone thiosemicarbazone series, namely di-2-pyridylketone 4,4 ...
Zhu-Ling Guo, Des R. Richardson, Danuta S. Kalinowski, Zaklina Kovacevic, Kian Cheng Tan-Un, Godfrey Chi-Fung Chan   +5 more
doaj   +1 more source

An N-myristoylated globin with a redox-sensing function that regulates the defecation cycle in Caenorhabditis elegans.

PLoS ONE, 2012
Globins occur in all kingdoms of life where they fulfill a wide variety of functions. In the past they used to be primarily characterized as oxygen transport/storage proteins, but since the discovery of new members of the globin family like neuroglobin ...
Lesley Tilleman, Sasha De Henau, Martje Pauwels, Nora Nagy, Isabel Pintelon, Bart P Braeckman, Karolien De Wael, Sabine Van Doorslaer, Dirk Adriaensen, Jean-Pierre Timmermans, Luc Moens, Sylvia Dewilde   +11 more
doaj   +1 more source