Results 131 to 140 of about 1,308,694 (239)

Ruxolitinib stopped before transplantation does not induce cytokine release in myelofibrosis. [PDF]

Cancer Immunol Immunother
Villar S, Curis E, Schlageter MH, Bosselut N, Charbonnier A, Rubio MT, Turlure P, Labussière H, Bay JO, Cornillon J, Vincent L, Orvain C, Kiladjian JJ, Michonneau D, Socié G, Robin M.   +15 more
europepmc   +1 more source

Bioengineering Strategies for Treating Neointimal Hyperplasia in Peripheral Vasculature: Innovations and Challenges

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John, Caitlyn Dang, Nidhi Reddy, Calvin Chao, Karen J. Ho, Bin Jiang   +5 more
wiley   +1 more source

The green tea component (-)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells. [PDF]

Front Pharmacol
Rosenthal R, Waesch A, Masete KV, Massarani AS, Schulzke JD, Hering NA.   +5 more
europepmc   +1 more source

Pericyte‐Assisted Vascular Lumen Organization in a Novel Dynamic Human Blood‐Brain Barrier‐on‐Chip Model

Advanced Healthcare Materials, EarlyView.
Organ‐on‐Chip (OoC) technology enables the precise modeling of the blood‐brain barrier (BBB). This study presents a microfluidic device that mimics brain microvessels, integrating co‐culture with pericytes and astrocytes under pulsatile flow. Results show that perivascular cells modulate endothelial morphology, promoting lumen formation and barrier ...
Vita Guarino, Elisabetta Perrone, Elisa De Luca, Alberto Rainer, Maura Cesaria, Alessandra Zizzari, Monica Bianco, Giuseppe Gigli, Lorenzo Moroni, Valentina Arima   +9 more
wiley   +1 more source

Neural representation of cytokines by vagal sensory neurons. [PDF]

Nat Commun
Huerta TS, Chen AC, Chaudhry S, Tynan A, Morgan T, Park K, Adamovich-Zeitlin R, Haider B, Li JH, Nagpal M, Zanos S, Pavlov VA, Brines M, Zanos TP, Chavan SS, Tracey KJ, Chang EH.   +16 more
europepmc   +1 more source

A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper presents a microphysiological system containing an array of individually addressable living corneal tissues constructed using primary human cells. The bioengineered eye model can simulate acute exposure of the human cornea to different types of environmental toxicants and provides a novel platform for visualization and quantitative ...
Se‐jeong Kim, Ning Guo, Zong Yao Tan, Xing Gao, Pouria Fattahi, Haijiao Liu, Jeehan Chang, Mousa Younesi, Selice Jung, Yewhan Chung, Minkyung Song, Michelle Jung, Dan Dongeun Huh   +12 more
wiley   +1 more source

Linking Epitope-Specific T-Cell Receptors to IFNγ Secretion Using Nanovial Technology. [PDF]

Eur J Immunol
van den Dijssel J, Menon T, McQuilten HA, Eltherington O, Gonzalez A, Baghdasarian S, Soemardy C, Di Carlo D, van Gisbergen KPJM, Ten Brinke A, van de Sandt CE.   +10 more
europepmc   +1 more source

Precision Photothermal Therapy at Mild Temperature: NIR‐II Imaging‐Guided, H2O2‐Responsive Stealth Nanobomb

Advanced Healthcare Materials, EarlyView.
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma, Qihang Ding, Yue Wang, Zhiwei Zhang, Yuding Zhang, Hui Shi, Lintao Cai, Ping Gong, Pengfei Zhang, Zhen Cheng, Jong Seung Kim   +10 more
wiley   +1 more source

Functional immune profiling of hyper- and hypo-inflammatory subphenotypes of critical illness: a secondary analysis. [PDF]

Front Immunol
Halstead ES, McKeone DJ, Samuelsen AM, Zhou S, Bonavia AS.   +4 more
europepmc   +1 more source

Antioxidant and Anti‐Senescence Polyvinyl Alcohol‐Gallic Acid Supramolecular Hydrogels for Stem Cell Culture

Advanced Healthcare Materials, EarlyView.
The PVA‐GA hydrogel is formed through hydrogen bonding between PVA hydroxyl groups and GA galloyl units, enabling sustainable GA release and its extended biological activity. The hydrogel scavenges ROS to reduce oxidative stress, preventing mitochondrial damage from excessive ROS, mitigating hADSC senescence, and preserving VEGF secretion, offering a ...
Yiduo Zhou, Matías L. Picchio, Yan Nie, Lei Wang, Oihane Sanz, Yue Liu, Xun Xu, Lukas Prantl, Oliver Felthaus, Weiwei Wang, Marcelo Calderón, Nan Ma   +11 more
wiley   +1 more source