Implantation of fibroblasts transfected with human granulocyte colony- stimulating factor cDNA into mice as a model of cytokine-supplement gene therapy [PDF]
, 1989 Kenzaburo Tani +9 more
openalex +1 more source
An inflammatory cytokine signature predicts COVID-19 severity and survival
Nature Network Boston, 2020 D. D. Del Valle +31 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun +5 more
wiley +1 more source
Inflammatory cytokines induce synthesis and secretion of gro protein and a neutrophil chemotactic factor but not β2-microglobulin in human synovial cells and fibroblasts [PDF]
, 1989 E.E. Golds, Patrizia Mason, P Nyirkos
openalex +1 more source
The pathogenesis and treatment of the `Cytokine Storm' in COVID-19
Journal of Infection, 2020 Q. Ye, Bili Wang, Jian-hua Mao
semanticscholar +1 more source
SensRORing cholesterol to drive protumoral myelopoiesis
Molecular Oncology, EarlyView.Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley +1 more source
Food and Agricultural Immunology, 2019 Portulaca oleracea L. is a traditional oriental medicine known for its pharmacological effects. The present study aimed to investigate the immunostimulatory effects of PPCE on cyclophosphamide-stimulated rat model and in isolated spleen cells. The result
Young Mi Park +14 more
doaj +1 more source
Maintenance of immune homeostasis through ILC/T cell interactions
Frontiers in Immunology, 2015 Innate lymphoid cells (ILCs) have emerged as a new family of immune cells with crucial functions in innate and adaptive immunity. ILC subsets mirror the cytokine and transcriptional profile of CD4+ T helper (TH) cell subsets. Hence, group 1 (ILC1), group
Nicole evon Burg +2 more
doaj +1 more source
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. [PDF]
, 1988 Aihao Ding +2 more
openalex +1 more source
ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome. [PDF]
, 2015 Backgrounds and aims4-6 million people die of enteric infections each year. After invading intestinal epithelial cells, enteric bacteria encounter phagocytes.
Casanova, James E +9 more
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