Results 111 to 120 of about 1,176,895 (316)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Both cyclooxygenase- and cytokine-mediated inflammation are associated with carotid intima-media thickness

, 2007
BACKGROUND: Common carotid artery intima-media thickness (CCA-IMT) is a valid index of atherosclerosis, which is viewed as an inflammatory disease.
Basu, Samar,, Wohlin, Martin,, Larsson, Anders,, Lind, Lars,, Helmersson, Johanna,, Arnlöv, Johan,, Andrén, Bertil,, Sundström, Johan,, Vessby, Bengt,   +8 more
core   +1 more source

Effects of chronic ascariasis and trichuriasis on cytokine production and gene expression in human blood: a cross-sectional study. [PDF]

, 2011
BACKGROUND: Chronic soil-transmitted helminth (STH) infections are associated with effects on systemic immune responses that could be caused by alterations in immune homeostasis.
Cooper, Philip J, Broncano, N, Reina Ortiz, Miguel, Miguel Reina Ortiz, Schreiber Fernanda, David J Lewis, Alexander Neal, Lewis, David J, Chico, ME, Benitez Susana, David J. Lewis, Vaca Maritza, Nely Broncano, Chico, Martha E, Dougan Gordon, Reina Ortiz, M, Fernanda Schreiber, Martha E. Chico, Schreiber, F, Alexander, N, Lewis, DJ, Philip J. Cooper, Gordon Dougan, Cooper Philip J., Dougan, Gordon, Neal Alexander, Vaca, Maritza, Benitez, S, Vaca, M, Martha E Chico, Benitez, Susana, Philip J Cooper, Broncano Nely, Alexander, Neal, Maritza Vaca, Susana Benitez, Dougan, G, Lewis David J., Schreiber, Fernanda, Cooper, PJ, Reina Ortiz Miguel, Cooper, Philip, Broncano, Nely, Chico Martha E.   +43 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Apoptosis-induced tolerance. Role of the novel cytokine IL-38

, 2022
S.109-110Introduction: Necrotic cell death triggers inflammation, whereas apoptosis contributes to its resolution. Interleukin-1 (IL-1) family cytokines are key players in this interaction and are produced by necrotic cells to induce sterile inflammation.
Putyrski, M., Brüne, B., Han, Y., Wittig, I., Ernst, A., Mora, J., Weigert, A.   +6 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Moderate exercise training modulates cytokine profile and sleep in elderly people [PDF]

, 2012
Aging causes several physiological alterations, including alterations in sleep. It is possible that difficulty sleeping can be exacerbated by increased inflammation in older individuals. Moderate exercise training may be a modality of non-pharmacological
Grassmann, Viviane [UNIFESP], Viana, Valter Antonio Rocha [UNIFESP], Mello, Marco Tulio de [UNIFESP], Santana, Marcos Gonçalves de [UNIFESP], Santos, Ronaldo Vagner Thomatieli dos [UNIFESP], Tufik, Sergio [UNIFESP], Boscolo, Rita Aurélia [UNIFESP], Lira, Fábio Santos de [UNIFESP]   +7 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection [PDF]

, 2011
Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Nashwa Abousamra, Azza Azza Abdel-Aziz, Mona Elhadidy, Mohamed Abd-elmaksoud, Yahia Gad, Nasser Mousa   +5 more
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