Results 261 to 270 of about 799,218 (270)

Is a "Cytokine Storm" Relevant to COVID-19?

JAMA Internal Medicine, 2020
In its most severe form, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), leads to a life-threatening pneumonia and acute respiratory distress syndrome (ARDS).
P. Sinha, M. Matthay, C. Calfee
semanticscholar   +1 more source

Interleukin-6: A Masterplayer in the Cytokine Network

Oncology, 2020
Interleukin-6 (IL-6) is a member of the pro-inflammatory cytokine family, induces the expression of a variety of proteins responsible for acute inflammation, and plays an important role in the proliferation and differentiation of cells in humans.
P. Uciechowski, W. Dempke
semanticscholar   +1 more source

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity.

Annual Review of Immunology, 1995
Interleukin-12 (IL-12) is a heterodimeric cytokine produced mostly by phagocytic cells in response to bacteria, bacterial products, and intracellular parasites, and to some degree by B lymphocytes.
G. Trinchieri
semanticscholar   +1 more source

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines.

Immunity, 2005
J. Schmitz, Alexander M. Owyang, E. Oldham, Yaoli Song, E. Murphy, T. Mcclanahan, G. Zurawski, M. Moshrefi, J. Qin, Xiaoxia Li, D. Gorman, J. Fernando Bazan, R. Kastelein, Schering-Plough Biopharma   +13 more
semanticscholar   +1 more source

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

Nature, 1994
John C. Lee, J. Laydon, P. Mcdonnell, T. Gallagher, Sanjay Kumar, D. Green, D. Mcnulty, Mary Jane Blumenthal, J. Keys, Scott W. Land vatter, J. Strickler, M. McLaughlin, I. R. Siemens, S. Fisher, G. P. Livi, J. White, J. Adams, P. Young   +17 more
semanticscholar   +1 more source

IL-6 as a keystone cytokine in health and disease

Nature Immunology, 2015
C. Hunter, Simon A. Jones
semanticscholar   +1 more source

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

Nature, 2003
D. Cua, J. Sherlock, Yi Chen, C. Murphy, Barbara Joyce, B. Seymour, L. Lucian, W. To, Sylvia Kwan, T. Churakova, S. Zurawski, M. Wiekowski, S. Lira, D. Gorman, R. Kastelein, J. Sedgwick   +15 more
semanticscholar   +1 more source

Cytokine storm and sepsis disease pathogenesis

Seminars in Immunopathology, 2017
B. Chousterman, F. Swirski, G. Weber
semanticscholar   +1 more source

Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer

Nature reviews. Immunology, 2018
Simon A. Jones, B. Jenkins
semanticscholar   +1 more source

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization

Nature Network Boston, 1999
Tomono Takahashi, C. Kalka, H. Masuda, Donghui Chen, Marcy Silver, M. Kearney, M. Magner, J. Isner, T. Asahara   +8 more
semanticscholar   +1 more source