Results 291 to 300 of about 1,542,731 (346)

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

Advanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs, Alexander Stoegner, Mateo G. Vasconez Martínez, Markus M. Schreiner, Melanie Cezanne, Ruth Gruebl‐Barabas, Bettina Rodriguez‐Molina, Juergen Alphonsus, Silvia Hayer, Richard Lass, Iris Gerner, Florien Jenner, Wolfgang Holnthoner, Stefan Toegel, Peter Ertl, Hans P. Kiener, Reinhard Windhager, Mario Rothbauer   +17 more
wiley   +1 more source

Identification of three T cell-related genes as diagnostic and prognostic biomarkers for triple-negative breast cancer and exploration of potential mechanisms. [PDF]

Front Genet
He ZC, Song ZZ, Wu Z, Lin PF, Wang XX.
europepmc   +1 more source

Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis

Advanced Healthcare Materials, EarlyView.
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo, Bo Li, Hongyi Li, Yi Chen, Qin Yuan, Mingju Shui, Hefeng Zhou, Wei Hao, Shengpeng Wang   +8 more
wiley   +1 more source

KDM6A downregulation promotes tumor-prone cytokines expression in cancer-associated fibroblasts by activating enhancers. [PDF]

Cell Death Dis
Zhang J, Xiang S, Liu D, Pei X, Chen M, Zhao Y, Wang Y, Wang Q, Kang L, Yu Z, Mi J, Xiong W.   +11 more
europepmc   +1 more source

Investigating the Role of the Sinus Microbiome and Cytokine Profile in the SNOT-22 Response After Functional Endoscopic Sinus Surgery in Chronic Rhinosinusitis Patients. [PDF]

J Clin Med
Hoying D, Sangwan N, Chaaban MR.
europepmc   +1 more source

Relationship between biologic therapy and cytokine levels in patients with inflammatory arthritis. [PDF]

Medicine (Baltimore)
Zhang Z, Zhou BH, Hu L, Li MC, Chang D, Dou X.   +5 more
europepmc   +1 more source

Cytokines and diseases. Cytokines and fever.

Nihon Naika Gakkai Zasshi, 1991
openaire   +3 more sources

Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants. [PDF]

Virol J
Kam TT, Bui CHT, Yeung HW, Wong PCH, Chin AWH, Nicholls JM, Peiris M, Hui KPY, Poon LLM, Chan MCW.   +9 more
europepmc   +1 more source

Myeloid cell genome-wide screen identifies variants associated with Mycobacterium tuberculosis-induced cytokine transcriptional responses. [PDF]

J Clin Invest
Ivie JJ, Dill-McFarland KA, Simmons JD, Peterson GJ, Benchek PH, Mayanja-Kizza H, Veith LE, Agata M, Ha DT, Nghia HD, Boom WH, Stein CM, Khor CC, Thwaites GE, Hai HT, Thuong NT, Chang X, Dunstan SJ, Hawn TR.   +18 more
europepmc   +1 more source