Results 31 to 40 of about 2,261,376 (387)

Engineering cytokine therapeutics

open access: yesNature Reviews Bioengineering, 2023
Cytokines have pivotal roles in immunity, making them attractive as therapeutics for a variety of immune-related disorders. However, the widespread clinical use of cytokines has been limited by their short blood half-lives and severe side effects caused ...
Jeroen Deckers   +15 more
semanticscholar   +1 more source

Curcumin Differs from Tetrahydrocurcumin for Molecular Targets, Signaling Pathways and Cellular Responses

open access: yesMolecules, 2014
Curcumin (diferuloylmethane), a golden pigment from turmeric, has been linked with antioxidant, anti-inflammatory, anticancer, antiviral, antibacterial, and antidiabetic properties. Most of the these activities have been assigned to methoxy, hydroxyl, α,
Bharat B. Aggarwal   +2 more
doaj   +1 more source

Cardiac Extracellular Vesicles (EVs) Released in the Presence or Absence of Inflammatory Cues Support Angiogenesis in Different Manners [PDF]

open access: yes, 2019
Cells release extracellular vesicles (EVs) to communicate in a paracrine manner with other cells, and thereby influence processes, such as angiogenesis.
Beez, Christien Madlen   +6 more
core   +1 more source

Immunopharmacological aspects of the cytokine system

open access: yesБюллетень сибирской медицины, 2019
Cytokines represent a unique family of endogenous polypeptide mediators of intercellular interaction. From an immunopharmacological point of view cytokines can be marked out as a new, separate immunoregulatory molecule system and have some common ...
A. S. Simbirtsev
doaj   +1 more source

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]

open access: yes, 2020
Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea   +6 more
core   +1 more source

Serum cholestenoic acid as a potential marker of pulmonary cholesterol homeostasis

open access: yesJournal of Lipid Research, 2004
The conversion of cholesterol into the more polar metabolites 27-hydroxycholesterol (27-OH) and cholestenoic acid by the cytochrome P450 sterol 27-hydroxylase is a cholesterol-removal mechanism used by almost all cells.
Steve Meaney   +5 more
doaj   +1 more source

Environmental and microbial factors influence affective and cognitive behavior in C57BL/6 sub-strains

open access: yesFrontiers in Immunology, 2023
C57BL/6 mice are one of the most widely used inbred strains in biomedical research. Early separation of the breeding colony has led to the development of several sub-strains.
Nada Abdel Aziz   +10 more
doaj   +1 more source

Cytokine Modulation of Keratinocyte Cytokines

open access: yesJournal of Investigative Dermatology, 1990
There is increasing evidence that epidermal cytokines may have an important role in mediating inflammatory and immune responses in the skin. A number of cell types in the epidermis are capable of secreting cytokines including keratinocytes, Langerhans cells, melanocytic cells, and even Merkle cells.
Ansel, John   +7 more
openaire   +2 more sources

Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

open access: yesFrontiers in Immunology, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes coronavirus disease 2019 (COVID-19). As of 25 May 2020, the outbreak of COVID-19 has caused 347,192 deaths around the world.
Yujun Tang   +5 more
semanticscholar   +1 more source

Distinct cytokine profiles across trajectories of self-perceived cognitive impairment among early-stage breast cancer survivors. [PDF]

open access: yes, 2020
The aim of the current study is to identify distinct cytokine profiles in relation to self-perceived cognitive trajectories. In our study cohort (n = 128), early-stage breast cancer patients were categorized into no impairment reported, acute ...
Chan, Alexandre   +3 more
core   +1 more source

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