Results 41 to 50 of about 2,162,469 (384)
Frontiers in Immunology, 2020 Circadian rhythms are a very exquisite mechanism to influence on transcriptional levels and physiological activities of various molecules that affect cell metabolic pathways.
Masato Kubo, Masato Kubo
doaj +1 more source
Distinct cytokine profiles across trajectories of self-perceived cognitive impairment among early-stage breast cancer survivors. [PDF]
, 2020 The aim of the current study is to identify distinct cytokine profiles in relation to self-perceived cognitive trajectories. In our study cohort (n = 128), early-stage breast cancer patients were categorized into no impairment reported, acute ...
Chan, Alexandre +3 more
core +1 more source
Journal of Immunotherapy for Cancer, 2018 During the last decade the field of cancer immunotherapy has witnessed impressive progress. Highly effective immunotherapies such as immune checkpoint inhibition, and T-cell engaging therapies like bispecific T-cell engaging (BiTE) single-chain antibody ...
A. Shimabukuro-Vornhagen +8 more
semanticscholar +1 more source
Mycotoxins nivalenol and deoxynivalenol differently modulate cytokine mRNA expression in Jurkat T cells. [PDF]
, 2006 Deoxynivalenol (DON) and its hydroxylated form nivalenol (NIV) are Fusarium mycotoxins that occur in cereal grains alone or in combination. Several studies have shown that these metabolites affect lymphocyte functions.
BERGAMO P +4 more
core +1 more source
bioRxiv, 2020 The COVID-19 pandemic has caused significant morbidity and mortality. Currently, there is a critical shortage of proven treatment options and an urgent need to understand the pathogenesis of multi-organ failure and lung damage.
Rajendra Karki +15 more
semanticscholar +1 more source
Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes [PDF]
, 2019 Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need.
Evans-Molina, Carmella +4 more
core +1 more source
Immunity, 2019 Asthma is a chronic inflammatory airway disease associated with type 2 cytokines interleukin-4 (IL-4), IL-5, and IL-13, which promote airway eosinophilia, mucus overproduction, bronchial hyperresponsiveness (BHR), and immunogloubulin E (IgE) synthesis. However, only half of asthma patients exhibit signs of an exacerbated Type 2 response.
Hamida Hammad +3 more
openaire +3 more sources
Cytokine Networks in the Pathogenesis of Rheumatoid Arthritis
International Journal of Molecular Sciences, 2021 Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic systemic inflammation causing progressive joint damage that can lead to lifelong disability. The pathogenesis of RA involves a complex network of various cytokines and cells that
N. Kondo, T. Kuroda, D. Kobayashi
semanticscholar +1 more source
F1000Research, 2012 The recent development of mammalian target of rapamycin (mTOR) kinase domain inhibitors and genetic dissection of rapamycin-sensitive and -insensitive mTOR protein complexes (mTORC1 and mTORC2) have revealed that phosphorylation of the mTOR substrate 4E ...
Mark Livingstone, Michael Bidinosti
doaj +1 more source
libtissue - implementing innate immunity [PDF]
, 2006 In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems.
Aickelin, Uwe, Twycross, Jamie
core +3 more sources