Results 131 to 140 of about 5,332,469 (256)
Advanced Functional Materials, EarlyView.An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Engineering Vanderbilt; Vol. 45 No. 01, 2004
, 2004 Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of EngineeringSchool of ...
Vanderbilt University. School of Engineering
core
Discover OncologyChimeric antigen receptor (CAR) T-cell therapy has profoundly reshaped the therapeutic landscape for hematologic malignancies, achieving remarkable response rates in relapsed/refractory B-cell leukemias and lymphomas.
Mutaz Jamal Al-khreisat +8 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
Quantitative analysis of cytokine-induced hepatocellular death in the context of hepatotoxic therapeutics [PDF]
, 2009 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biological Engineering, 2009."February 2009." Cataloged from PDF version of thesis.Includes bibliographical references (p. 161-178).Numerous therapeutics, such as viral gene therapy vectors,
Cosgrove, Benjamin D. (Benjamin David)
core
Engineering Organ-on-a-Chip Systems for Cancer Immunotherapy: Strategies and Assay Integration
BioengineeringTranslating preclinical findings into effective clinical cancer immunotherapies remains a major challenge, mainly because conventional in vitro and animal models often fail to capture the complexity, dynamics, and species-specific features of human ...
Jie Wang, Zongjie Wang
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande +9 more
wiley +1 more source
Mechanisms by which interleukin-4 suppresses inflammatory cytokine production by activated human monocytes [PDF]
, 2011 Improving understanding of how inflammatory responses by monocytes and macrophages are regulated may aid in the development of more targeted therapies for chronic inflammatory disease.
Woodward, Eleanor
core
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Engineering Vanderbilt; Vol. 51, No. 02, 2010
, 2010 Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of Engineering.* 2 * from the dean * 6 * cover story - The Infinite to the Finite: Vanderbilt Researchers Imagine the Future of Imaging Science and ...
Vanderbilt University. School of Engineering
core