Results 111 to 120 of about 11,604 (173)

Regulation of immunological equilibrium by IL-6/STAT3 in glaucomatous irises and its effect on filtering bleb success. [PDF]

Indian J Ophthalmol
Sinha N, Dubey S, Pegu J, Sangwan VS, Tiwari A.   +4 more
europepmc   +1 more source

Characterization and localization of intracellular signals emanating from an oncogenic mutant of the cytokine receptor Gp130

, 2015
IL-6 is a major regulator of the acute phase response (APR) and signals via a hexameric complex comprising two molecules IL-6, IL-6Rα and gp130, respectively. Upon formation of the signaling complex cytoplasmic Tyr-residues of the receptor get phosphorylated by receptor associated Jaks leading to the initiation of two major signaling pathways: the Jak ...
openaire   +1 more source

A Novel Phosphoglucomutase-3 Gene Variant Causing Milder Phenotype in Two Families. [PDF]

J Clin Immunol
Gemici Karaaslan B, Benamar M, Ulas S, Aydemir S, Yesil G, Gezdirici A, Sari AA, Nepesov S, Cokugras H, Camcioglu Y, Ayaz A, Aydogmus C, Charbonnier LM, Chatila T, Kiykim A.   +14 more
europepmc   +1 more source

Gαi1 and Gαi3 mediate IL-11-induced signal transduction and are potential therapeutic targets for LUAD. [PDF]

Cell Death Dis
Luo G, Hu W, Yang J, Lu Z, Cui Y, Zeng W, Ding H, Li Q, Chen Z, Tong X, Ding C, Xu C, Zhao J.   +12 more
europepmc   +1 more source

Nano-Luciferase complementation assay of human herpesvirus 8 chemo/cytokine-receptor interactions. [PDF]

Sci Rep
Palande V, Roden RBS, Choi YB.
europepmc   +1 more source

Prostatic fibroblast reprogramming by Interleukin-30 activates prostate cancer metastasis programs. [PDF]

Mol Biomed
Ciummo SL, Sorrentino C, Marchetti S, Fieni C, Lanuti P, Di Carlo E.   +5 more
europepmc   +1 more source

Elevating Jak-STAT signaling via SOCS3 deletion sustains photoreceptor viability and visual function in mouse models of retinitis pigmentosa. [PDF]

Cell Commun Signal
Wang Y, Nusinowitz S, Yang XJ.
europepmc   +1 more source

Oncostatin-M ligand-based CAR-T therapy displays robust anti-tumor activity against osteosarcoma. [PDF]

BMC Med
Feinberg D, Uppin V, Eid S, Fritz C, Hitomi M, Radhakrishnan A, Klatt K, Choi SH, Myers JT, Bhatt A, Stearns D, Pateva I, Burke ZDC, Huang AY, Schwartz GK, Parameswaran R.   +15 more
europepmc   +1 more source

Role of Interleukin-6 in Atherothrombosis and Myocardial Infarction. [PDF]

Curr Atheroscler Rep
Huse C, Gregersen I, Holme FA, Ueland T, Skjelland M, Aamodt AH, Dahl TB, Aukrust P, Halvorsen B.   +8 more
europepmc   +1 more source

IL-27: A Double-Edged Sword in Immune Regulation via JAK-STAT Orchestration. [PDF]

J Immunol Res
Zhang X, Feng C, Xu Y, Zeng Y, Luo Q, Qin J, Li T, Peng L, Zhang H, Dai H.   +9 more
europepmc   +1 more source