Results 251 to 260 of about 193,929 (276)

Tocilizumab for Steroid Pulse-Refractory Cytokine Release Syndrome in Chemotherapy With Durvalumab Plus Tremelimumab for NSCLC: A Case Report. [PDF]

JTO Clin Res Rep
Yamamoto K, Hirano K, Shimada T, Hata A.
europepmc   +1 more source

Effect of interferon induced transmembrane protein 1 ( IFITM1 ) upregulation to cytokine release syndrome in CAR-T-treated B-cell acute lymphoblastic leukemia. [PDF]

Chin Med J (Engl)
Du M, Zhang Y, Li C, Zhou F, Luo W, Tang L, Wu J, Jiang H, Wei Q, Lu C, Kou H, Hu Y, Mei H.   +12 more
europepmc   +1 more source

Clinical Pharmacology of Cytokine Release Syndrome with T-Cell-Engaging Bispecific Antibodies: Current Insights and Drug Development Strategies. [PDF]

Clin Cancer Res
Radtke KK, Bender BC, Li Z, Turner DC, Roy S, Belousov A, Li CC.   +6 more
europepmc   +1 more source

Cytokine release syndrome following chimeric antigen receptor T-cell therapy: Pathophysiology, clinical manifestations, and novel therapeutic approaches

Kirill V. Lepik, T. Yu. Dergacheva, Marina Popova, А. Н. Андрианов, M. Yu. Samsonov, Ivan Moiseev   +5 more
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A Novel Two-Part Mixture Model for the Incidence and Time Course of Cytokine Release Syndrome After Elranatamab Dosing in Multiple Myeloma Patients. [PDF]

Clin Pharmacol Ther
Irby D, Hibma J, Elmeliegy M, Wang D, Vandendries E, Poels K, Shtylla B, Williams JH.   +7 more
europepmc   +1 more source

Discovery, delineation, and therapeutic targeting of a hyper-translation pathway driving cytokine release syndrome

Xingxian Liu, Jiaqi Li, Yajing Zhang, Yang S. Liu, Chunmeng Wang, Yao Wang, Yunqi Liu, Yuzhuo Yang, Yao Su, Youxue Lu, Wenyan Wang, Yang-Xin Fu, Xin Lin, Deng Pan, Weidong Han, Xiaoyu Hu   +15 more
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The impact of obesity and its related underlying diseases on cytokine release syndrome and the efficacy of CAR-T therapy in treating B-cell malignancies. [PDF]

Ann Hematol
Du M, Mayombo RTM, Liu J, Zhang Y, Liao D, Hu Y, Mei H.   +6 more
europepmc   +1 more source

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Cytokine Release Syndrome Biology and Management

The Cancer Journal, 2021
Abstract The successful application of chimeric antigen receptor (CAR) T cells for the treatment of relapsed and refractory B-cell malignancies has ushered in a new frontier for the immunotherapy of cancer. Despite its successes, CAR T-cell therapy presents several challenges.
Dustin A, Cobb, Daniel W, Lee
openaire   +2 more sources

Druggable Targets in Cytokine Release Syndromes

Clinical Cancer Research, 2023
Summary Bispecific T-cell engagers and chimeric antigen receptor T cells share the problem of eliciting acute systemic inflammation episodes known as cytokine release syndrome. Knowledge on the sequential waves of cytokines that can be neutralized with clinically available agents is crucial to prevent or treat this condition without ...
Carlos Luri-Rey, Iñaki Eguren-Santamaria, Ignacio Matos, Pedro Berraondo, Ignacio Melero   +4 more
openaire   +2 more sources