Results 151 to 160 of about 71,915 (261)

The blood purification therapy-based strategy effectively rescued the severe falciparum malaria patient experiencing cytokine storm-driven MODS. [PDF]

Front Cell Infect Microbiol
Sun Y, Huang X, Hong B, Song J, Lu Y, Ma J, Wang X, Hu W, Zhang Y, Xuan H.   +9 more
europepmc   +1 more source

Involvement of the miR‐128‐3p/KDM3A/NLRP3 Axis in High Glucose‐Induced Inflammatory Injury in Retinal Endothelial Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explores the regulatory mechanism of the miR‐128‐3p in diabetic retinopathy (DR)‐associated inflammatory injury. A cellular model of DR was established by inducing immortalized human retinal endothelial cells (IM‐HRECs) with high‐glucose (HG).
Wei‐Ming Wen, Jian‐Bo Feng, Yin‐Sheng Cai, Nan Lin, Fei Lv, Zhu‐Sheng Guo   +5 more
wiley   +1 more source

Analysis of the Innate Immune Response to Febrile UTI in Infants: Evidence of an Acute Cytokine Storm. [PDF]

Pediatr Infect Dis J
Ahmadi S, Rosenblad T, Sabari S, Linden M, Brandström P, Chao SM, Svanborg C, Ambite I, Ambite I.   +8 more
europepmc   +1 more source

Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen, Tao‐Tao Shi, Dan‐Yang Hu, Xiao‐Na Su, Jian‐Xiang Jin, Mao‐Song Chen, Hao Wang, Wei Chen   +7 more
wiley   +1 more source

Hemophagocytic Lymphohistiocytosis Gene Variants in Severe COVID-19 Cytokine Storm Syndrome. [PDF]

Viruses
Kamath A, Zhang M, Absher DM, Jackson LE, Chatham WW, Cron RQ.   +5 more
europepmc   +1 more source

Calming the cytokine storm [PDF]

Nature, 2011
openaire   +1 more source

Systematic Deciphering of ATBC Nephrotoxicity Mechanisms via Machine Learning and Single‐Cell Analysis

Medicine Bulletin, EarlyView.
This study elucidates the nephrotoxic mechanism of acetyl tributyl citrate (ATBC) by integrating network toxicology, machine learning, and single‑cell multi‑omics analysis to systematically decipher the molecular mechanisms and cell‑type‑specific regulatory networks underlying ATBC‑induced kidney injury. First, a protein‑protein interaction network was
Yimao Wu, Yalun Liang, Jintao Liang, Wenlong Sun, Qian Zhang, Meng‐Yao Li   +5 more
wiley   +1 more source

Cytokine storm and microvascular fate: mechanistic insights into endothelial injury in thrombotic microangiopathies. [PDF]

Ann Med Surg (Lond)
Obeagu EI.
europepmc   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

Medicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei, Yunli Xu, Tianjiao Zhang, Shuyu Xu, Haonan Wang, Yuan Wang, Xinxin Xie, Xiaolong Liang   +7 more
wiley   +1 more source

Multi-organ pathology in a small porcine model of cytokine storm syndrome characteristics. [PDF]

Front Immunol
Jin J, Fan L, Chen R, Lin X, Zhang S, Zhu M.   +5 more
europepmc   +1 more source