Results 41 to 50 of about 458,337 (361)

Cytology cell blocks are suitable for immunohistochemical testing for PD-L1 in lung cancer

Annals of Oncology, 2018
Background PD-L1 immunohistochemistry (IHC) testing is usually carried out on tissue blocks from core needle biopsy or surgical resections. In this study, we assessed the feasibility of using cytology cell blocks for PD-L1 IHC assay. Methods A total of
H. Wang, H. Wang, J. Agulnik, J. Agulnik, G. Kasymjanova, G. Kasymjanova, A. Wang, P. Jiménez, V. Cohen, V. Cohen, D. Small, C. Pepe, L. Sakr, P. Fiset, Manon Auger, S. Camilleri-Broët, M. A. E. Din, George Chong, L. V. Kempen, L. V. Kempen, A. Spatz   +20 more
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Endothelial-mesenchymal crosstalk drives osteogenic differentiation of human osteoblasts through Notch signaling

Cell Communication and Signaling
Background Angiogenesis and osteogenesis are closely interrelated. The interaction between endothelial and bone-forming cells, such as osteoblasts, is crucial for normal bone development and repair.
Daria Perepletchikova, Polina Kuchur, Liubov Basovich, Irina Khvorova, Arseniy Lobov, Kseniia Azarkina, Nikolay Aksenov, Svetlana Bozhkova, Vitaliy Karelkin, Anna Malashicheva   +9 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Transcriptomic response of marine dinoflagellate Prorocentrum cordatum to phosphorus deficiency

Scientific Reports
Phosphorus is crucial for marine phytoplankton viability as a key biogenic element. Under phosphorus deficiency, dinoflagellates exhibit changes in their feeding regime, alterations in transporters functioning, a reduction in cell proliferation rate and,
Vera Kalinina, Olga Palii, Pavel Safonov, Sergei Skarlato, Mariia Berdieva   +4 more
doaj   +1 more source

Prognostic significance of peritoneal lavage cytology in staging gastric cancer: systematic review and meta-analysis

Gastric Cancer, 2017
BackgroundPeritoneal cytology has been used as a part of the cancer staging of gastric cancer patients. The primary aim of this systematic review was to evaluate the value of peritoneal cytology as part of the staging of gastric cancer and survival ...
S. Jamel, S. Markar, G. Malietzis, A. Acharya, T. Athanasiou, G. Hanna   +5 more
semanticscholar   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Cytology Smears in the Era of Molecular Biomarkers in Non-Small Cell Lung Cancer: Doing More With Less.

Archives of Pathology & Laboratory Medicine, 2018
CONTEXT - The rapid advances in targeted therapies in non-small cell lung cancer (NSCLC) make the optimization and implementation of cytology specimens for molecular testing a priority.
M. Lozano, J. Echeveste, M. Abengózar, L. Mejías, M. Idoate, A. Calvo, Carlos E. De Andrea   +6 more
semanticscholar   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Hippocampal glucocorticoid receptor and microRNA gene expression and serum cortisol concentration in foxes selected for behavior toward humans

Вавиловский журнал генетики и селекции, 2018
In many cases, stress reactivity is one of the important bases of aggressive behavior. It appears as if reduced stress reactivity underlies an abrupt decrease in aggression towards man in domesticated animals.
V. Yu. Ovchinnikov, E. V. Antonov, G. V. Vasilyev, S. G. Shihevich, D. V. Shepeleva, Yu. E. Herbeck   +5 more
doaj   +1 more source