Results 211 to 220 of about 44,623 (260)

Measurement of Tumor Cytolysis by Macrophages

Current Protocols in Immunology, 2011
AbstractThis unit describes two different protocols for the measurement of tumor cytolysis by macrophages. Traditionally, cytotoxicity assays have relied on the use of radioactive isotopes. In Basic Protocol 1, cytotoxic activity is measured by the release into the culture supernatant of a radioisotope that had been incorporated by the target cell and ...
Mónica, Escórcio-Correia, Thorsten, Hagemann   +1 more
openaire   +2 more sources

Cytolysis in normal and complicated pregnancy

American Journal of Obstetrics and Gynecology, 1973
Abstract Cytolysis of vaginal cells in normal and complicated pregnancies was graded as mild, moderate, or marked. The series studied comprised 1,439 normal pregnancies, 287 cases of threatened abortion, 51 cases of hyperemesis gravidarum, 258 cases of toxemia, 213 cases of postmaturity, and 94 cases of diabetes.
B, Bercovici, A, Schechter, J, Golan
openaire   +2 more sources

Cytolysis of Eosinophils in Nasal Secretions

Annals of Otology, Rhinology & Laryngology, 2003
It is still unknown how eosinophils degranulate in nasal mucus. Currently, cytolysis is being reevaluated as the mode of degranulation of eosinophils in allergic nasal mucosa. To examine whether eosinophils migrating to the nasal mucus degranulate by cytolysis, we sampled nasal mucus from 9 patients with nasal allergy and observed it under electron and
Kensuke, Watanabe, Toshihiro, Misu, Satomi, Inoue, Hideo, Edamatsu   +3 more
openaire   +2 more sources

A Central Role of Perforin in Cytolysis?

Annual Review of Immunology, 1991
Studies on the gene structure, on the transcript, and on perforin protein are reviewed, including intracellular trafficking. Perforin transcription is tightly regulated and specific for CTL and NK. Two independent pathways for perforin induction exist, only one of them being IL-2 independent. Perforin expression in vitro and in vivo correlates with the
E R, Podack, H, Hengartner, M G, Lichtenheld   +2 more
openaire   +2 more sources

Effects of Cortisol on Immune Cytolysis

Pathologia et Microbiologia, 2008
High concentrations of cortisol effectivelyabolish the lysis of sheep red cells induced by cytotoxic antibody and complement in vitro. This effect lies in the ability of the steroid molecules to pack closely among the aliphalic chains of the phospholipid monolayers present in cell membranes, thereby preventing the net uptake of ions by damaged cells ...
G, Tolone, L, Bonasera, A, Bellavia, F, Ferina   +3 more
openaire   +2 more sources

Pathways for Cytolysis

1995
List of Contents.- Perforin and Granzymes: Crucial Effector Molecules in Cytolytic T Lymphocyte and Natural Killer Cell-Mediated Cytotoxicity.- Fas-Based T Cell-Mediated Cytotoxicity.- Structure and Biogenesis of Lytic Granules.- The Role of CD28 Costimulation Cytotoxic in the Generation of T Lymphocytes.- Degranulating Cytotoxic Lymphocytes Inflict ...
openaire   +1 more source

Lymphoid Cells as Effectors of Immunologic Cytolysis

Hospital Practice, 1977
Two classes of cytotoxic lymphocytes are described. One is composed of cytotoxic T lymphocytes (CTL), which have antigen specificity derived from prior immunization. The lymphocytes of the other class--the K cells--derive their limited specificity from affinity for antibodies on the surface of the target cells.
openaire   +3 more sources

Immune cytolysis of mouse thymic lymphocytes

Transplantation, 1963
Summary Immune cytolysis was carried out by mixing a suspension of mouse thymic lymphocytes containing 97 to 99% viable cells with complement and various dilutions of rabbit antiserum or isoantiserum. Cellular integrity was determined after incubation for 2 hr at 37° C, by use of vital staining.
openaire   +2 more sources

T Lymphocyte-Mediated Cytolysis — A Comprehensive Theory I. The Mechanism of CTL-Mediated Cytolysis

1982
The mechanism(s) by which cytotoxic T lymphocyte (CTL) cause lethal and irreversible damage to target cells (TC) has been the subject of considerable research during the past 10–15 years. A number of mechanisms have been proposed, examined, and either have been disproved or have generally not been pursued for lack of convincing experimental evidence in
G, Berke, W R, Clark
openaire   +2 more sources

The Prevalence of Liver Cytolysis in Children With Helicobacter pylori Infection

Children, 2022
Ancuţa Lupu, Cristina Gavrilovici, Elena Tarca   +2 more
exaly