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Measurement of Immune Cytolysis
Nature, 1964IMMUNE lysis of tissue cells is more difficult to measure than immune haemolysis because the material lost by lysing cells is not coloured, as haemoglobin is. Greon, Fleischer, Barrow and Goldberg1 among others have shown that during immune lysis of ascites tumour cells, cytoplasmic nucleic acid is released from the cells, mainly as nucleoprotein.
J A, ROMEYN, C, RIGBY
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Perforin and Lymphocyteâmediated Cytolysis
Immunological Reviews, 1995We have discussed in the previous sections the recent progress made toward elucidating the regulatory mechanism of perforin gene transcription and the domain structure of the perforin molecule. It appears that the expression of perforin is, at least partially, controlled at the transcription level through the interaction between killer cell-specific ...
C C, Liu, P M, Persechini, J D, Young
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Transfusion Medicine Reviews, 2006
In addition to alloimmune and autoimmune cell lysis, a third category of immune destruction of blood cells should be recognized. This additional immunologic response occurs when cells or tissues are injured by immunologic reactions in which the cells act as "innocent bystanders." One mechanism by which an immune response to an exogenous antigen leads ...
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In addition to alloimmune and autoimmune cell lysis, a third category of immune destruction of blood cells should be recognized. This additional immunologic response occurs when cells or tissues are injured by immunologic reactions in which the cells act as "innocent bystanders." One mechanism by which an immune response to an exogenous antigen leads ...
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Lymphocyte-Mediated Cytolysis and Disease
New England Journal of Medicine, 1996Lymphocytes are equipped to eradicate noxious agents (microbes, cancer cells, and grafts) that disturb the body's equilibrium, but when their cellular activity is excessive, the results are harmful. The list of abnormalities known to be caused by excessive lymphocyte activity is extensive.
C C, Liu, L H, Young, J D, Young
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