Results 91 to 100 of about 3,288,372 (337)

Cytomegalovirus Infection in Children in Japan [PDF]

, 1968
Shunzo Chiba, Masami Ohsaki, Hisaaki Hanazono, Tooru Nakao   +3 more
openalex   +1 more source

NPR1 Promotes Lipid Droplet Lipolysis to Enhance Mitochondrial Oxidative Phosphorylation and Fuel Gastric Cancer Metastasis

Advanced Science, EarlyView.
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu, Jie Zhang, Hengxing Chen, Haobin Hou, Huanjie Chen, Rongman Xie, Yanlei Chen, Jian Zhang, Dehua Liu, Leping Yan, Rui L. Reis, Joaquim M. Oliveira, Yulong He, Li Zhong, Qinbo Cai, Dongjie Yang   +15 more
wiley   +1 more source

The problem of congenital cytomegalovirus infection

Журнал инфектологии, 2016
This paper comprises a review of up-to-date literature devoted to the problem of congenital cytomegalovirus infection, its epidemiology and pathogenesis.
R. A. Ivanova, V. V. Vasiliev, S. M. Vikhnina, M. Yu. Boboshko, G. M. Ushakova   +4 more
doaj  

Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer

Advanced Science, EarlyView.
Dysregulated RNA splicing is an underappreciated molecular feature of cancer. By integrating murine and cellular models with patient specimens of lung adenocarcinoma, this study demonstrates that RAC1B, rather than RAC1A isoform, promotes tumorigenesis and presents a potent therapeutic target for lung cancer. Mechanistically, RAC1B preferentially binds
Yueren Yan, Ning Wang, Bowen Xing, Min Yang, Jun Shang, Yufang Bao, Lixing Xiao, Ningxia Zhang, Yunpeng Ren, Chunnan Liu, Yuting Chen, Han Han, Yunjian Pan, Lei Lv, Wei‐Xing Zong, Hongbin Ji, Changyou Zhan, Zefeng Wang, Haiquan Chen, Yongbo Wang   +19 more
wiley   +1 more source

A Human Immuno‐Lung Organoid Model to Study Macrophage‐Mediated Lung Cell Senescence Upon SARS‐CoV‐2 Infection

Advanced Science, EarlyView.
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han, Dongliang Leng, Tuo Zhang, Jian Ge, Yinshan Fang, Tiankun Lu, Xue Dong, Manoj S Nair, Neranjan de Silva, Zhaowei Han, Tiancheng Jiao, Yuanhao Huang, Meiqi Zhao, Anjali Saqi, Hanina Hibshoosh, Zihe Meng, Jenny Z Xiang, Chendong Pan, Yanjie Sun, David D. Ho, Todd Evans, Jie Liu, Liuliu Yang, Jianwen Que, Shuibing Chen   +24 more
wiley   +1 more source

Synergistic effect on mortality in mice with murine cytomegalovirus and Pseudomonas aeruginosa, Staphylococcus aureus, or Candida albicans infections [PDF]

, 1976
John R. Hamilton, James C. Overall, L. A. Glasgow   +2 more
openalex   +1 more source

Sleep Deprivation Activates a Conserved Lactate‐H3K18la‐RORα Axis Driving Neutrophilic Inflammation Across Species

Advanced Science, EarlyView.
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou, Keyun Li, Xiezong Hu, Shuhao Fan, Yuxuan Gao, Xiaoshu Xue, Yu Bu, Haoyi Zhang, Yili Wang, Chunjiao Wei, Shangrong Zhang, Zhongwen Xie, Chao Liu, Peng Chen, Zongjun Yin, Dalong Ren   +15 more
wiley   +1 more source

Risk of Cytomegalovirus Infection and Disease after Umbilical Cord Blood Transplantation in Children

Canadian Journal of Infectious Diseases and Medical Microbiology, 2013
BACKGROUND: Pediatric data regarding cytomegalovirus (CMV) infections in pediatric patients receiving umbilical cord blood (UCB) transplantation are sparse.
Pierre Alex Crisinel, Michel Duval, Delphine Thuillard Crisinel, Brigitte Mallette, Nathalie Bellier, Marie-France Vachon, Laurence Dedeken, Céline Rousseau, Bruce Tapiero, Philippe Ovetchkine   +9 more
doaj   +1 more source

Cytomegalovirus Infections in the Atypical Host: A Case Series of Clinical Conundra. [PDF]

Cureus, 2023
Hassan KS, Idris A, Al Lawati BS, Balkhair A.   +3 more
europepmc   +1 more source

Immunoglobulin G to Virus-Specific Early Antigens in Congenital, Primary, and Reactivated Human Cytomegalovirus Infections [PDF]

, 1979

openalex   +1 more source